8W8

2,2,2-tris(fluoranyl)-~{N}-[(1~{R},2~{S})-1-[1-(4-fluorophenyl)indazol-5-yl]oxy-1-(3-methoxyphenyl)propan-2-yl]ethanamide


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Chemical Component Summary

Name2,2,2-tris(fluoranyl)-~{N}-[(1~{R},2~{S})-1-[1-(4-fluorophenyl)indazol-5-yl]oxy-1-(3-methoxyphenyl)propan-2-yl]ethanamide
Identifiers2,2,2-tris(fluoranyl)-~{N}-[(1~{R},2~{S})-1-[1-(4-fluorophenyl)indazol-5-yl]oxy-1-(3-methoxyphenyl)propan-2-yl]ethanamide
FormulaC25 H21 F4 N3 O3
Molecular Weight487.446
TypeNON-POLYMER
Isomeric SMILESC[C@@H]([C@@H](c1cccc(c1)OC)Oc2ccc3c(c2)cnn3c4ccc(cc4)F)NC(=O)C(F)(F)F
InChIInChI=1S/C25H21F4N3O3/c1-15(31-24(33)25(27,28)29)23(16-4-3-5-20(12-16)34-2)35-21-10-11-22-17(13-21)14-30-32(22)19-8-6-18(26)7-9-19/h3-15,23H,1-2H3,(H,31,33)/t15-,23-/m0/s1
InChIKeyFCNQMDSJHADDFT-WNSKOXEYSA-N

Chemical Details

Formal Charge0
Atom Count56
Chiral Atom Count2
Bond Count59
Aromatic Bond Count22

Drug Info: DrugBank

DrugBank IDDB12280 
NameAZD-5423
Groups investigational
DescriptionAZD5423 has been used in trials studying the basic science and treatment of Asthma, Bioavailability and AUC, and Chronic Obstructive Pulmonary Disease (COPD).
SynonymsAZD-5423
Categories
  • Acetates
  • Acids, Acyclic
  • Amides
  • Anti-Asthmatic Agents
  • Heterocyclic Compounds, Fused-Ring
CAS number1034148-04-3

Related Resource References

Resource NameReference
Pharos CHEMBL4072756
PubChem 24825740
ChEMBL CHEMBL4072756