ASN
ASPARAGINE
Find entries where: ASN
is present as a standalone ligand in 37 entries
as a non-polymer is covalently linked to polymer or other heterogen groups 15 entries
is present in a polymer sequence 218,935 entries
Chemical Component Summary | |
|---|---|
| Name | ASPARAGINE |
| Identifiers | (2S)-2,4-bis(azanyl)-4-oxidanylidene-butanoic acid |
| Formula | C4 H8 N2 O3 |
| Molecular Weight | 132.118 |
| Type | L-PEPTIDE LINKING |
| Isomeric SMILES | C([C@@H](C(=O)O)N)C(=O)N |
| InChI | InChI=1S/C4H8N2O3/c5-2(4(8)9)1-3(6)7/h2H,1,5H2,(H2,6,7)(H,8,9)/t2-/m0/s1 |
| InChIKey | DCXYFEDJOCDNAF-REOHCLBHSA-N |
Chemical Details | |
|---|---|
| Formal Charge | 0 |
| Atom Count | 17 |
| Chiral Atom Count | 1 |
| Bond Count | 16 |
| Aromatic Bond Count | 0 |
Drug Info: DrugBank
| DrugBank ID | DB00174 |
|---|---|
| Name | Asparagine |
| Groups |
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| Description | A non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue. It is biosynthesized from aspartic acid and ammonia by asparagine synthetase. (From Concise Encyclopedia Biochemistry and Molecular Biology, 3rd ed) |
| Synonyms |
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| Brand Names |
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| Indication | Used for nutritional supplementation, also for treating dietary shortage or imbalance. |
| Categories |
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| CAS number | 70-47-3 |
Drug Targets
| Name | Target Sequence | Pharmacological Action | Actions |
|---|---|---|---|
| Sodium-coupled neutral amino acid transporters | MMHFKSGLELTELQNMTVPEDDNISNDSNDFTEVENGQINSKFISDRESR... | unknown | inhibitor |
| Neutral amino acid transporter B(0) | MVADPPRDSKGLAAAEPTANGGLALASIEDQGAAAGGYCGSRDQVRRCLR... | unknown | |
| Asparagine synthetase [glutamine-hydrolyzing] | MCGIWALFGSDDCLSVQCLSAMKIAHRGPDAFRFENVNGYTNCCFGFHRL... | unknown | |
| Asparagine--tRNA ligase, cytoplasmic | MVLAELYVSDREGSDATGDGTKEKPFKTGLKALMTVGKEPFPTIYVDSQK... | unknown | |
| Isoaspartyl peptidase/L-asparaginase | MNPIVVVHGGGAGPISKDRKERVHQGMVRAATVGYGILREGGSAVDAVEG... | unknown | substrate |
| View More | |||
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison
T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS.
Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682
Related Resource References
| Resource Name | Reference |
|---|---|
| PubChem | 6992089, 6267 |
| ChEMBL | CHEMBL58832 |
| ChEBI | CHEBI:17196, CHEBI:58048 |
| CCDC/CSD | LIRLUW, ILUXOC, WAMPOQ, LIRMAD, LIRMEH, HUDJIA, COTZOB, NUYFUI01, NUYFUI, SUYWEP, MAPFIT, AYAQID |
| COD | 2227303 |
