ATM

3'-AZIDO-3'-DEOXYTHYMIDINE-5'-MONOPHOSPHATE

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is present as a standalone ligand in 9 entries

as a non-polymer is covalently linked to polymer or other heterogen groups 2 entries

is present in a polymer sequence 8 entries

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Chemical Component Summary
Name	3'-AZIDO-3'-DEOXYTHYMIDINE-5'-MONOPHOSPHATE
Identifiers	[(2S,3S,5R)-3-azido-5-(5-methyl-2,4-dioxo-pyrimidin-1-yl)oxolan-2-yl]methyl dihydrogen phosphate
Formula	C₁₀ H₁₄ N₅ O₇ P
Molecular Weight	347.221
Type	DNA LINKING
Isomeric SMILES	CC1=CN(C(=O)NC1=O)[C@H]2C[C@@H]([C@H](O2)COP(=O)(O)O)N=[N+]=[N-]
InChI	InChI=1S/C10H14N5O7P/c1-5-3-15(10(17)12-9(5)16)8-2-6(13-14-11)7(22-8)4-21-23(18,19)20/h3,6-8H,2,4H2,1H3,(H,12,16,17)(H2,18,19,20)/t6-,7+,8+/m0/s1
InChIKey	OIFWQOKDSPDILA-XLPZGREQSA-N

Chemical Details
Formal Charge	0
Atom Count	37
Chiral Atom Count	3
Bond Count	38
Aromatic Bond Count	0

Drug Info: DrugBank

DrugBank ID	DB03666
Name	Zidovudine monophosphate
Groups	experimental
Synonyms	3'-Azido-3'-deoxythymidine 5'-phosphate ZDVMP Zidovudine monophosphate Zdv 5'-monophosphate AZTMP Zidovudine 5'-monophosphate 3'-Azido-2',3'-deoxythymidine 5'-monophosphate
Categories	Deoxyribonucleosides Deoxyribonucleotides Dideoxynucleosides Nucleic Acids, Nucleotides, and Nucleosides Nucleosides Nucleotides Pyrimidine Nucleosides Pyrimidine Nucleotides Pyrimidines
CAS number	29706-85-2

Drug Targets

Name	Target Sequence	Pharmacological Action	Actions
Thymidylate kinase	MAARRGALIVLEGVDRAGKSTQSRKLVEALCAAGHRAELLRFPERSTEIG...	unknown
Thymidylate kinase	MLIAIEGVDGAGKRTLVEKLSGAFRAAGRSVATLAFPRYGQSVAADIAAE...	unknown

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682