BFR

N-butyl-N'-(diaminomethylidene)guanidine


Toggle HydrogenToggle Labels

Chemical Component Summary

NameN-butyl-N'-(diaminomethylidene)guanidine
SynonymsBuformin
Identifiers1-[bis(azanyl)methylidene]-3-butyl-guanidine
FormulaC6 H15 N5
Molecular Weight157.217
TypeNON-POLYMER
Isomeric SMILES[H]/N=C(\NCCCC)/N=C(N)N
InChIInChI=1S/C6H15N5/c1-2-3-4-10-6(9)11-5(7)8/h2-4H2,1H3,(H6,7,8,9,10,11)
InChIKeyXSEUMFJMFFMCIU-UHFFFAOYSA-N

Chemical Details

Formal Charge0
Atom Count26
Chiral Atom Count0
Bond Count25
Aromatic Bond Count0

Drug Info: DrugBank

DrugBank IDDB04830 
NameBuformin
Groups
  • investigational
  • withdrawn
DescriptionBuformin is an anti-diabetic drug of the biguanide class, chemically related to metformin and phenformin. It was withdrawn from the market in most countries due to a high risk of causing lactic acidosis.
Synonyms
  • Buformin hydrochloride
  • Buformin
  • Buformine
  • Buformina
  • Buforminum
Categories
  • Alimentary Tract and Metabolism
  • Amidines
  • Biguanides
  • Blood Glucose Lowering Agents
  • Drugs Used in Diabetes
ATC-CodeA10BA03
CAS number692-13-7

Drug Targets

NameTarget SequencePharmacological ActionActions
Solute carrier family 22 member 1MPTVDDILEQVGESGWFQKQAFLILCLLSAAFAPICVGIVFLGFTPDHHC...unknownsubstrate
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682

Related Resource References

Resource NameReference
PubChem 2468
ChEMBL CHEMBL39736
ChEBI CHEBI:3209