BRE

2-BIPHENYL-4-YL-6-FLUORO-3-METHYL-QUINOLINE-4-CARBOXYLIC ACID

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is present as a standalone ligand in 1 entries

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Chemical Component Summary
Name	2-BIPHENYL-4-YL-6-FLUORO-3-METHYL-QUINOLINE-4-CARBOXYLIC ACID
Synonyms	BREQUINAR ANALOG
Identifiers	6-fluoro-3-methyl-2-(4-phenylphenyl)quinoline-4-carboxylic acid
Formula	C₂₃ H₁₆ F N O₂
Molecular Weight	357.377
Type	NON-POLYMER
Isomeric SMILES	Cc1c(c2cc(ccc2nc1c3ccc(cc3)c4ccccc4)F)C(=O)O
InChI	InChI=1S/C23H16FNO2/c1-14-21(23(26)27)19-13-18(24)11-12-20(19)25-22(14)17-9-7-16(8-10-17)15-5-3-2-4-6-15/h2-13H,1H3,(H,26,27)
InChIKey	WYKKHJQZENLZID-UHFFFAOYSA-N

Chemical Details
Formal Charge	0
Atom Count	43
Chiral Atom Count	0
Bond Count	46
Aromatic Bond Count	25

Drug Info: DrugBank

DrugBank ID	DB03480
Name	Brequinar Analog
Groups	experimental
Synonyms	Brequinar Analog

Drug Targets

Name	Target Sequence	Pharmacological Action	Actions
Dihydroorotate dehydrogenase (quinone), mitochondrial	MAWRHLKKRAQDAVIILGGGGLLFASYLMATGDERFYAEHLMPTLQGLLD...	unknown

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682