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6-BROMOINDIRUBIN-3'-OXIME


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Chemical Component Summary

Name6-BROMOINDIRUBIN-3'-OXIME
Synonyms(3E)-6'-BROMO-2,3'-BIINDOLE-2',3(1H,1'H)-DIONE 3-OXIME
Identifiers(3Z)-6-bromo-3-[(3E)-3-hydroxyimino-1H-indol-2-ylidene]-1H-indol-2-one
FormulaC16 H10 Br N3 O2
Molecular Weight356.174
TypeNON-POLYMER
Isomeric SMILESc1ccc2c(c1)/C(=N\O)/C(=C/3\c4ccc(cc4NC3=O)Br)/N2
InChIInChI=1S/C16H10BrN3O2/c17-8-5-6-9-12(7-8)19-16(21)13(9)15-14(20-22)10-3-1-2-4-11(10)18-15/h1-7,18,22H,(H,19,21)/b15-13-,20-14+
InChIKeyDDLZLOKCJHBUHD-WAVHTBQISA-N

Chemical Details

Formal Charge0
Atom Count32
Chiral Atom Count0
Bond Count35
Aromatic Bond Count12

Drug Info: DrugBank

DrugBank IDDB03444 
Name6-bromoindirubin-3'-oxime
Groups experimental
Synonyms
  • 6-bromoindirubin-3'-oxime
  • (2Z,3E)-6'-bromo-2,3'-biindole-2',3(1H,1'H)-dione 3-oxime
  • 6-BIO
  • (2Z,3E)-6-Bromoindirubin-3'-oxime
Categories
  • Amines
  • Glycogen Synthase Kinase 3, antagonists & inhibitors
  • Heterocyclic Compounds, Fused-Ring
  • Hydroxylamines
CAS number667463-62-9

Drug Targets

NameTarget SequencePharmacological ActionActions
Glycogen synthase kinase-3 betaMSGRPRTTSFAESCKPVQQPSAFGSMKVSRDKDGSKVTTVVATPGQGPDR...unknown
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682