Chemical Component Summary

NameCAMPHOR
Identifiers(1R,4R)-1,7,7-trimethylbicyclo[2.2.1]heptan-6-one
FormulaC10 H16 O
Molecular Weight152.233
TypeNON-POLYMER
Isomeric SMILESCC1([C@@H]2CC[C@]1(C(=O)C2)C)C
InChIInChI=1S/C10H16O/c1-9(2)7-4-5-10(9,3)8(11)6-7/h7H,4-6H2,1-3H3/t7-,10+/m1/s1
InChIKeyDSSYKIVIOFKYAU-XCBNKYQSSA-N

Chemical Details

Formal Charge0
Atom Count27
Chiral Atom Count2
Bond Count28
Aromatic Bond Count0

Drug Info: DrugBank

DrugBank IDDB01744 
NameCamphor
Groups
  • approved
  • withdrawn
DescriptionCamphor is a bicyclic monoterpene ketone found widely in plants, especially _Cinnamomum camphora_. It is used topically as a skin antipruritic and as an anti-infective agent. When ingested, camphor has a rapid onset of toxic effects, and camphorated oil is the product most often responsible for its toxicity. The FDA ruled that camphorated oil could not be marketed in the United States and that no product could contain a concentration higher than 11%. It appears in the list of drug products withdrawn or removed from the market for safety or effectiveness.[A254252,L43942] However, camphor can be found in several nonprescription medications at lower concentrations.[A254252]
Synonyms
  • (R)-camphor
  • Camphor(D)
  • Camphor oil
  • Camphor D-form
  • (R)-(+)-camphor
Brand Names
  • Neptune Ice
  • PlusCBD Pain Cream (Arthritis) 2oz
  • CBDMEDIC Back and Neck Pain Relief
  • Yao Shen Gao Pain Relieving Plaster
  • Salonpas - Pls Top
Categories
  • Anti-Infective Agents
  • Anti-Infective Agents, Local
  • Antipruritics and Local Anesthetics
  • Basic Lotions and Liniments
  • Bicyclic Monoterpenes
ATC-CodeC01EB02
CAS number464-49-3

Drug Targets

NameTarget SequencePharmacological ActionActions
Transient receptor potential cation channel subfamily V member 1MKKWSSTDLGAAADPLQKDTCPDPLDGDPNSRPPPAKPQLSTAKSRTRLF...unknownagonist,activator
Transient receptor potential cation channel subfamily V member 3MKAHPKEMVPLMGKRVAAPSGNPAILPEKRPAEITPTKKSAHFFLEIEGF...unknownagonist,activator
Transient receptor potential cation channel subfamily A member 1MKRSLRKMWRPGEKKEPQGVVYEDVPDDTEDFKESLKVVFEGSAYGLQNF...unknowninhibitor
Transient receptor potential cation channel subfamily M member 8MSFRAARLSMRNRRNDTLDSTRTLYSSASRSTDLSYSESDLVNFIQANFK...unknownactivator
Camphor 5-monooxygenaseMTTETIQSNANLAPLPPHVPEHLVFDFDMYNPSNLSAGVQEAWAVLQESN...unknownsubstrate
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682

Related Resource References

Resource NameReference
PubChem 159055
ChEMBL CHEMBL504760
ChEBI CHEBI:15396
CCDC/CSD UGAHUF, PAMFOB