CMP

ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE

Find entries where: CMP

is present as a standalone ligand in 154 entries

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Chemical Component Summary
Name	ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE
Synonyms	CYCLIC AMP; CAMP
Identifiers	(1R,4R,6S,7R,8R)-8-(6-aminopurin-9-yl)-4-hydroxy-4-oxo-3,5,9-trioxa-4$l^{5}-phosphabicyclo[4.3.0]nonan-7-ol
Formula	C₁₀ H₁₂ N₅ O₆ P
Molecular Weight	329.206
Type	NON-POLYMER
Isomeric SMILES	c1nc(c2c(n1)n(cn2)[C@H]3[C@@H]([C@H]4[C@H](O3)CO[P@](=O)(O4)O)O)N
InChI	InChI=1S/C10H12N5O6P/c11-8-5-9(13-2-12-8)15(3-14-5)10-6(16)7-4(20-10)1-19-22(17,18)21-7/h2-4,6-7,10,16H,1H2,(H,17,18)(H2,11,12,13)/t4-,6-,7-,10-/m1/s1
InChIKey	IVOMOUWHDPKRLL-KQYNXXCUSA-N

Chemical Details
Formal Charge	0
Atom Count	34
Chiral Atom Count	5
Bond Count	37
Aromatic Bond Count	10

Drug Info: DrugBank

DrugBank ID	DB02527
Name	Cyclic adenosine monophosphate
Groups	experimental
Description	Cyclic adenosine monophosphate (cAMP, cyclic AMP or 3'-5'-cyclic adenosine monophosphate) is a molecule that is important in many biological processes; it is derived from adenosine triphosphate (ATP).
Synonyms	Cyclic adenylic acid Cyclic AMP 3',5'-cyclic AMP Adenosine 3',5'-phosphate Cyclic adenosine monophosphate Adenosine 3',5'-cyclic phosphate cAMP AMPC Adenosine 3',5'-cyclic monophosphate
Categories	Adenine Nucleotides Cyclic AMP Heterocyclic Compounds, Fused-Ring Nucleic Acids, Nucleotides, and Nucleosides Nucleotides Nucleotides, Cyclic OAT1/SLC22A6 Substrates OAT3/SLC22A8 Substrates Purine Nucleotides Purines Ribonucleotides
CAS number	60-92-4

Drug Targets

Name	Target Sequence	Pharmacological Action	Actions
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2	MDARGGGGRPGESPGATPAPGPPPPPPPAPPQQQPPPPPPPAPPPGPGPA...	unknown
cAMP-dependent protein kinase type I-alpha regulatory subunit	MESGSTAASEEARSLRECELYVQKHNIQALLKDSIVQLCTARPERPMAFL...	unknown
cAMP-dependent protein kinase type II-beta regulatory subunit	MSIEIPAGLTELLQGFTVEVLRHQPADLLEFALQHFTRLQQENERKGTAR...	unknown
cAMP-activated global transcriptional regulator CRP	MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAV...	unknown
Adenylate cyclase	MSLQQRNFGETGDLILGTQNQEQNLPETSAPVGTLARRKGTISTFLAPLT...	unknown
Cyclic nucleotide-gated potassium channel mll3241	MSVLPFLRIYAPLNAVLAAPGLLAVAALTIPDMSGRSRLALAALLAVIWG...	unknown
Multidrug resistance-associated protein 4	MLPVYQEVKPNPLQDANLCSRVFFWWLNPLFKIGHKRRLEEDDMYSVLPE...	unknown	substrate,inhibitor
Multidrug resistance-associated protein 5	MKDIDIGKEYIIPSPGYRSVRERTSTSGTHRDREDSKFRRTRPLECQDAL...	unknown	inhibitor
ATP-binding cassette sub-family C member 11	MTRKRTYWVPNSSGGLVNRGIDIGDDMVSGLIYKTYTLQDGPWSQQERNP...	unknown	substrate,inhibitor
Solute carrier family 22 member 6	MAFNDLLQQVGGVGRFQQIQVTLVVLPLLLMASHNTLQNFTAAIPTHHCR...	unknown	substrate
Solute carrier family 22 member 8	MTFSEILDRVGSMGHFQFLHVAILGLPILNMANHNLLQIFTAATPVHHCR...	unknown	substrate
Solute carrier family 22 member 7	MGFEELLEQVGGFGPFQLRNVALLALPRVLLPLHFLLPIFLAAVPAHRCA...	unknown	substrate
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Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682