DK1

5,7-DICHLORO-4-HYDROXYQUINOLINE-2-CARBOXYLIC ACID


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Chemical Component Summary

Name5,7-DICHLORO-4-HYDROXYQUINOLINE-2-CARBOXYLIC ACID
SynonymsDCKA; 5,7-DICHLOROKYNURENIC ACID
Identifiers5,7-dichloro-4-hydroxy-quinoline-2-carboxylic acid
FormulaC10 H5 Cl2 N O3
Molecular Weight258.058
TypeNON-POLYMER
Isomeric SMILESc1c(cc(c2c1nc(cc2O)C(=O)O)Cl)Cl
InChIInChI=1S/C10H5Cl2NO3/c11-4-1-5(12)9-6(2-4)13-7(10(15)16)3-8(9)14/h1-3H,(H,13,14)(H,15,16)
InChIKeyBGKFPRIGXAVYNX-UHFFFAOYSA-N

Chemical Details

Formal Charge0
Atom Count21
Chiral Atom Count0
Bond Count22
Aromatic Bond Count11

Drug Info: DrugBank

DrugBank IDDB01931 
Name5,7-Dichlorokynurenic acid
Groups experimental
Synonyms
  • 5,7-Dichloroquinurenic acid
  • 5,7-Dichorokynurenic acid
  • 5,7-Dichlorokynurenic acid
  • 5,7-Dcka
Categories
  • Excitatory Amino Acid Agents
  • Excitatory Amino Acid Antagonists
  • Heterocyclic Compounds, Fused-Ring
  • Hydroxyquinolines
  • Neurotransmitter Agents
CAS number131123-76-7

Drug Targets

NameTarget SequencePharmacological ActionActions
Glutamate receptor ionotropic, NMDA 1MSTMRLLTLALLFSCSVARAACDPKIVNIGAVLSTRKHEQMFREAVNQAN...unknown
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682

Related Resource References

Resource NameReference
PubChem 1779, 5288072
ChEMBL CHEMBL50267
ChEBI CHEBI:107660
CCDC/CSD RAVMUW
COD 2006203