DT

THYMIDINE-5'-MONOPHOSPHATE

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is present as a standalone ligand in 13 entries

as a non-polymer is covalently linked to polymer or other heterogen groups 1 entries

is present in a polymer sequence 10,951 entries

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Chemical Component Summary
Name	THYMIDINE-5'-MONOPHOSPHATE
Identifiers	[(2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxo-pyrimidin-1-yl)oxolan-2-yl]methyl dihydrogen phosphate
Formula	C₁₀ H₁₅ N₂ O₈ P
Molecular Weight	322.208
Type	DNA LINKING
Isomeric SMILES	CC1=CN(C(=O)NC1=O)[C@H]2C[C@@H]([C@H](O2)COP(=O)(O)O)O
InChI	InChI=1S/C10H15N2O8P/c1-5-3-12(10(15)11-9(5)14)8-2-6(13)7(20-8)4-19-21(16,17)18/h3,6-8,13H,2,4H2,1H3,(H,11,14,15)(H2,16,17,18)/t6-,7+,8+/m0/s1
InChIKey	GYOZYWVXFNDGLU-XLPZGREQSA-N

Chemical Details
Formal Charge	0
Atom Count	36
Chiral Atom Count	3
Bond Count	37
Aromatic Bond Count	0

Drug Info: DrugBank

DrugBank ID	DB01643
Name	Thymidine monophosphate
Groups	experimental
Description	5-Thymidylic acid. A thymine nucleotide containing one phosphate group esterified to the deoxyribose moiety.
Synonyms	Thymidylate Thymidine monophosphate TMP Thymidine-5'-phosphate 2'-deoxy-5-methyluridine 5'-(dihydrogen phosphate) Thymidine-5'-Monophosphate Thymidine 5'-phosphoric acid dTMP Thymidine mononucleotide ribothymidine 5'-monophosphate 5'-TMP thymidine 5'-(dihydrogen phosphate) Thymidine 5'-phosphate Thymidine-5'-monophosphoric acid 5-Methyl-dUMP Deoxyribosylthymine monophosphate Deoxythymidine monophosphate 5'-Thymidylic acid Thymidylic acid
Categories	Deoxyribonucleotides Nucleic Acids, Nucleotides, and Nucleosides Nucleotides Pyrimidine Nucleotides Pyrimidines Thymine Nucleotides
CAS number	365-07-1

Drug Targets

Name	Target Sequence	Pharmacological Action	Actions
Thymidylate kinase	MLIAIEGVDGAGKRTLVEKLSGAFRAAGRSVATLAFPRYGQSVAADIAAE...	unknown	product of
Thymidylate kinase	MAARRGALIVLEGVDRAGKSTQSRKLVEALCAAGHRAELLRFPERSTEIG...	unknown	product of
Thymidylate synthase	MPVAGSELPRRPLPPAAQERDAEPRPPHGELQYLGQIQHILRCGVRKDDR...	unknown	product of
DNA topoisomerase 1	MGKALVIVESPAKAKTINKYLGSDYVVKSSVGHIRDLPTSGSAAKKSADS...	unknown
Thymidylate synthase	MLEQPYLDLAKKVLDEGHFKPDRTHTGTYSIFGHQMRFDLSKGFPLLTTK...	unknown	product of
PCZA361.16	MQARKLAVDGAIEFTPRVFADDRGLLILPYQEEAFVEAHGGPLFRVAQTI...	unknown
DNA polymerase III subunit epsilon	MSTAITRQIVLDTETTGMNQIGAHYEGHKIIEIGAVEVVNRRLTGNNFHV...	unknown
Glucose-1-phosphate thymidylyltransferase	MKRKGIILAGGSGTRLHPATLAISKQLLPVYDKPMIYYPLSTLMLAGIRE...	unknown
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Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682