DTV

(2S,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL



Chemical Component Summary

Name(2S,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL
Identifiers(2S,3S)-1,4-bis-sulfanylbutane-2,3-diol
FormulaC4 H10 O2 S2
Molecular Weight154.251
TypeNON-POLYMER
Isomeric SMILESC([C@H]([C@@H](CS)O)O)S
InChIInChI=1S/C4H10O2S2/c5-3(1-7)4(6)2-8/h3-8H,1-2H2/t3-,4-/m1/s1
InChIKeyVHJLVAABSRFDPM-QWWZWVQMSA-N

Chemical Details

Formal Charge0
Atom Count18
Chiral Atom Count2
Bond Count17
Aromatic Bond Count0

Drug Info: DrugBank

DrugBank IDDB02184 
NameD-1,4-dithiothreitol
Groups experimental
DescriptionA reagent commonly used in biochemical studies as a protective agent to prevent the oxidation of SH (thiol) groups and for reducing disulphides to dithiols. [PubChem]
Synonyms
  • D-1,4-dithiothreitol
  • D-threo-1,4-dimercapto-2,3-butanediol
  • (2S,3S)-1,4-dimercaptobutane-2,3-diol
  • D-DTT

Drug Targets

NameTarget SequencePharmacological ActionActions
6,7-dimethyl-8-ribityllumazine synthaseMKGGAGVPDLPSLDASGVRLAIVASSWHGKICDALLDGARKVAAGCGLDD...unknown
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682

Related Resource References

Resource NameReference
PubChem 446094
ChEMBL CHEMBL1232392
ChEBI CHEBI:42170