FSE

3,7,3',4'-TETRAHYDROXYFLAVONE


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Chemical Component Summary

Name3,7,3',4'-TETRAHYDROXYFLAVONE
SynonymsFisetin; 2-(3,4-DIHYDROXYPHENYL)-3,7-DIHYDROXY-4H-CHROMEN-4-ONE
Identifiers2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-chromen-4-one
FormulaC15 H10 O6
Molecular Weight286.236
TypeNON-POLYMER
Isomeric SMILESc1cc(c(cc1C2=C(C(=O)c3ccc(cc3O2)O)O)O)O
InChIInChI=1S/C15H10O6/c16-8-2-3-9-12(6-8)21-15(14(20)13(9)19)7-1-4-10(17)11(18)5-7/h1-6,16-18,20H
InChIKeyXHEFDIBZLJXQHF-UHFFFAOYSA-N

Chemical Details

Formal Charge0
Atom Count31
Chiral Atom Count0
Bond Count33
Aromatic Bond Count12

Drug Info: DrugBank

DrugBank IDDB07795 
NameFisetin
Groups experimental
Synonyms
  • 3,7,3',4'-tetrahydroxyflavone
  • 2-(3,4-Dihydroxyphenyl)-3,7-dihydroxy-4H-1-benzopyran-4-one
  • Fisetin
  • 5-Desoxyquercetin
  • 3,3',4',7-Tetrahydroxyflavone
Categories
  • Benzopyrans
  • Chromones
  • Flavonoids
  • Heterocyclic Compounds, Fused-Ring
  • Pyrans
CAS number528-48-3

Drug Targets

NameTarget SequencePharmacological ActionActions
Cyclin homologMADSPNRLNRAKIDSTTMKDPRVLNNLKLRELLLPKFTSLWEIQTEVTVD...unknown
Cyclin-dependent kinase 6MEKDGLCRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTG...unknown
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682

Related Resource References

Resource NameReference
Pharos CHEMBL31574
PubChem 5281614
ChEMBL CHEMBL31574
ChEBI CHEBI:42567
CCDC/CSD ZIKNOY01, JOPVAN, JOQGED, ZIKNOY
COD 7211140, 7218269, 7218270, 7211139