GBL

GAMMA-BUTYROLACTONE


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Chemical Component Summary

NameGAMMA-BUTYROLACTONE
SynonymsDIHYDROFURAN-2(3H)-ONE
Identifiersoxolan-2-one
FormulaC4 H6 O2
Molecular Weight86.089
TypeNON-POLYMER
Isomeric SMILESC1CC(=O)OC1
InChIInChI=1S/C4H6O2/c5-4-2-1-3-6-4/h1-3H2
InChIKeyYEJRWHAVMIAJKC-UHFFFAOYSA-N

Chemical Details

Formal Charge0
Atom Count12
Chiral Atom Count0
Bond Count12
Aromatic Bond Count0

Drug Info: DrugBank

DrugBank IDDB04699 
Namegamma-Butyrolactone
Groups
  • experimental
  • illicit
DescriptionOne of the furans with a carbonyl thereby forming a cyclic lactone. It is an endogenous compound made from gamma-aminobutyrate and is the precursor of gamma-hydroxybutyrate. It is also used as a pharmacological agent and solvent.
Synonyms
  • 1,4-lactone
  • 4-butyrolactone
  • 4-hydroxybutyric acid lactone
  • γ-butyrolactone
  • dihydrofuran-2(3h)-one
Categories
  • 4-Butyrolactone
  • Compounds used in a research, industrial, or household setting
  • Furans
  • Lactones
  • Solvents
CAS number96-48-0

Drug Targets

NameTarget SequencePharmacological ActionActions
O-GlcNAcase NagJMKRKMLKRLLTSAFACMFIANGLITTTVRAVGPKTGEENQVLVPNLNPTP...unknown
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682

Related Resource References

Resource NameReference
PubChem 7302
ChEMBL CHEMBL95681
ChEBI CHEBI:42639
CCDC/CSD BICGUP, LUBMUS, AHULIB, FOMNAX, TITDAE, EYUHOV, GUZTOK, ZULJUO, QAHJOC, PECYIJ, QAVKIL, QAVJUW, KAWSAG
COD 2100197