GSH
GLUTATHIONE
Find entries where: GSH
is present as a standalone ligand in 404 entries
as a non-polymer is covalently linked to polymer or other heterogen groups 79 entries
Chemical Component Summary | |
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Name | GLUTATHIONE |
Identifiers | (2S)-2-azanyl-5-[[(2R)-1-(2-hydroxy-2-oxoethylamino)-1-oxidanylidene-3-sulfanyl-propan-2-yl]amino]-5-oxidanylidene-pentanoic acid |
Formula | C10 H17 N3 O6 S |
Molecular Weight | 307.323 |
Type | NON-POLYMER |
Isomeric SMILES | C(CC(=O)N[C@@H](CS)C(=O)NCC(=O)O)[C@@H](C(=O)O)N |
InChI | InChI=1S/C10H17N3O6S/c11-5(10(18)19)1-2-7(14)13-6(4-20)9(17)12-3-8(15)16/h5-6,20H,1-4,11H2,(H,12,17)(H,13,14)(H,15,16)(H,18,19)/t5-,6-/m0/s1 |
InChIKey | RWSXRVCMGQZWBV-WDSKDSINSA-N |
Chemical Details | |
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Formal Charge | 0 |
Atom Count | 37 |
Chiral Atom Count | 2 |
Bond Count | 36 |
Aromatic Bond Count | 0 |
Drug Info: DrugBank
DrugBank ID | DB00143 |
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Name | Glutathione |
Groups |
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Description | A tripeptide with many roles in cells. It conjugates to drugs to make them more soluble for excretion, is a cofactor for some enzymes, is involved in protein disulfide bond rearrangement and reduces peroxides. |
Synonyms |
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Brand Names |
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Indication | For nutritional supplementation, also for treating dietary shortage or imbalance |
Categories |
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ATC-Code | V03AB32 |
CAS number | 70-18-8 |
Drug Targets
Name | Target Sequence | Pharmacological Action | Actions |
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Aldose reductase | MASRLLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQ... | unknown | |
Matrix metalloproteinase-9 | MSLWQPLVLVLLVLGCCFAAPRQRQSTLVLFPGDLRTNLTDRQLAEEYLY... | unknown | |
Cytochrome P450 3A4 | MALIPDLAMETWLLLAVSLVLLYLYGTHSHGLFKKLGIPGPTPLPFLGNI... | unknown | |
Glutathione peroxidase | MTTQLRVVHLLPLLLACFVQTSPKQEKMKMDCHKDEKGTIYDYEAIALNK... | unknown | |
Glutathione reductase, mitochondrial | MALLPRALSAGAGPSWRRAARAFRGFLLLLPEPAALTRALSRAMACRQEP... | unknown | |
View More |
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison
T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS.
Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682
Related Resource References
Resource Name | Reference |
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Pharos | CHEMBL1543 |
PubChem | 124886, 25246407 |
ChEMBL | CHEMBL1543 |
ChEBI | CHEBI:60836, CHEBI:16856 |