Chemical Component Summary

NameN-OMEGA-HYDROXY-L-ARGININE
Identifiers(2S)-2-amino-5-[(N-hydroxycarbamimidoyl)amino]pentanoic acid
FormulaC6 H14 N4 O3
Molecular Weight190.2
TypeL-PEPTIDE LINKING
Isomeric SMILESC(C[C@@H](C(=O)O)N)CNC(=N)NO
InChIInChI=1S/C6H14N4O3/c7-4(5(11)12)2-1-3-9-6(8)10-13/h4,13H,1-3,7H2,(H,11,12)(H3,8,9,10)/t4-/m0/s1
InChIKeyFQWRAVYMZULPNK-BYPYZUCNSA-N

Chemical Details

Formal Charge0
Atom Count27
Chiral Atom Count1
Bond Count26
Aromatic Bond Count0

Drug Info: DrugBank

DrugBank IDDB03144 
NameN(5)-[(hydroxyamino)(imino)methyl]-L-ornithine
Groups experimental
Synonyms
  • N(5)-[(hydroxyamino)(imino)methyl]-L-ornithine
  • N-omega-hydroxy-L-arginine
Categories
  • Amino Acids
  • Amino Acids, Basic
  • Amino Acids, Diamino
  • Amino Acids, Peptides, and Proteins

Drug Targets

NameTarget SequencePharmacological ActionActions
Nitric oxide synthase, endothelialMGNLKSVAQEPGPPCGLGLGLGLGLCGKQGPATPAPEPSRAPASLLPPAP...unknown
Nitric oxide synthase oxygenaseMEEKEILWNEAKAFIAACYQELGKEEEVKDRLADIKSEIDLTGSYVHTKE...unknown
Nitric oxide synthase, inducibleMACPWKFLFKTKFHQYAMNGEKDINNNVEKAPCATSSPVTQDDLQYHNLS...unknown
Arginase-1MSAKSRTIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQECDVKDY...unknown
Nitric oxide synthase, brainMEDHMFGVQQIQPNVISVRLFKRKVGGLGFLVKERVSKPPVIISDLIRGG...unknown
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682

Related Resource References

Resource NameReference
PubChem 123895, 25799416
ChEMBL CHEMBL260629
ChEBI CHEBI:47821, CHEBI:60111, CHEBI:47819, CHEBI:47822, CHEBI:43088