IQP

1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE


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Chemical Component Summary

Name1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE
SynonymsH-7
Identifiers5-[(1R,2S)-2-methylpiperazin-1-yl]sulfonylisoquinoline
FormulaC14 H17 N3 O2 S
Molecular Weight291.369
TypeNON-POLYMER
Isomeric SMILESC[C@H]1CNCC[N@]1S(=O)(=O)c2cccc3c2ccnc3
InChIInChI=1S/C14H17N3O2S/c1-11-9-16-7-8-17(11)20(18,19)14-4-2-3-12-10-15-6-5-13(12)14/h2-6,10-11,16H,7-9H2,1H3/t11-/m0/s1
InChIKeyBDVFVCGFMNCYPV-NSHDSACASA-N

Chemical Details

Formal Charge0
Atom Count37
Chiral Atom Count1
Bond Count39
Aromatic Bond Count11

Drug Info: DrugBank

DrugBank IDDB07996 
Name5-(2-methylpiperazine-1-sulfonyl)isoquinoline
Groups experimental
Synonyms
  • 1-(5-Isoquinolinylsulfonyl)-2-methylpiperazine
  • 1-(5-Isoquinolinesulfonyl)-2-methylpiperazine
  • 5-(2-methylpiperazine-1-sulfonyl)isoquinoline
Categories
  • Enzyme Inhibitors
  • Heterocyclic Compounds, Fused-Ring
  • Isoquinolines
  • Piperazines
  • Sulfonamides
CAS number84477-87-2

Drug Targets

NameTarget SequencePharmacological ActionActions
cAMP-dependent protein kinase catalytic subunit alphaMGNAAAAKKGSEQESVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTL...unknown
cAMP-dependent protein kinase inhibitor alphaMTDVETTYADFIASGRTGRRNAIHDILVSSASGNSNELALKLAGLDINKT...unknown
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682

Related Resource References

Resource NameReference
PubChem 449240
ChEMBL CHEMBL1233654