J8D

5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one


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Chemical Component Summary

Name5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one
Synonymsdiosmetin
Identifiers2-(4-methoxy-3-oxidanyl-phenyl)-5,7-bis(oxidanyl)chromen-4-one
FormulaC16 H12 O6
Molecular Weight300.263
TypeNON-POLYMER
Isomeric SMILESCOc1ccc(cc1O)C2=CC(=O)c3c(cc(cc3O2)O)O
InChIInChI=1S/C16H12O6/c1-21-13-3-2-8(4-10(13)18)14-7-12(20)16-11(19)5-9(17)6-15(16)22-14/h2-7,17-19H,1H3
InChIKeyMBNGWHIJMBWFHU-UHFFFAOYSA-N

Chemical Details

Formal Charge0
Atom Count34
Chiral Atom Count0
Bond Count36
Aromatic Bond Count12

Drug Info: DrugBank

DrugBank IDDB11259 
NameDiosmetin
Groups experimental
DescriptionDiosmetin is an O-methylated flavone and the aglycone part of the flavonoid glycosides diosmin that occurs naturally in citrus fruits [A27231]. Pharmacologically, diosmetin is reported to exhibit anticancer, antimicrobial, antioxidant, oestrogenic and anti-inflamatory activities [A27231]. It also acts as a weak TrkB receptor agonist [A27230].
Synonyms
  • Salinigricoflavonol
  • 5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-benzopyrone
  • 3',5,7-trihydroxy-4'-methoxyflavone
  • Diosmetin
  • Luteolin 4'-methyl ether
Brand Names
  • Gongjinhyang Seol Whitening
  • Isaknox X202 Whitening Secret Essence
  • Isa Knox Wxii Plus Whitening Revolution Serum
  • Gongjinhyang Seol Whitening Essence
  • Whoo Gongjinhyang Seol Whitening Jin Essence
Categories
  • Benzopyrans
  • Chromones
  • Heterocyclic Compounds, Fused-Ring
  • Pyrans
CAS number520-34-3

Related Resource References

Resource NameReference
Pharos CHEMBL90568
PubChem 5281612
ChEMBL CHEMBL90568
ChEBI CHEBI:4630