LKP
trans-4-{(1R)-2-[(5S)-6-fluoro-5H-imidazo[5,1-a]isoindol-5-yl]-1-hydroxyethyl}cyclohexan-1-ol
Find entries where: LKP
is present as a standalone ligand in 1 entries
Chemical Component Summary | |
|---|---|
| Name | trans-4-{(1R)-2-[(5S)-6-fluoro-5H-imidazo[5,1-a]isoindol-5-yl]-1-hydroxyethyl}cyclohexan-1-ol |
| Synonyms | Navoximod |
| Identifiers | 4-[(1~{R})-2-[(5~{S})-6-fluoranyl-5~{H}-imidazo[1,5-b]isoindol-5-yl]-1-oxidanyl-ethyl]cyclohexan-1-ol |
| Formula | C18 H21 F N2 O2 |
| Molecular Weight | 316.37 |
| Type | NON-POLYMER |
| Isomeric SMILES | c1cc-2c(c(c1)F)[C@@H](n3c2cnc3)C[C@H](C4CCC(CC4)O)O |
| InChI | InChI=1S/C18H21FN2O2/c19-14-3-1-2-13-16-9-20-10-21(16)15(18(13)14)8-17(23)11-4-6-12(22)7-5-11/h1-3,9-12,15,17,22-23H,4-8H2/t11-,12-,15-,17+/m0/s1 |
| InChIKey | YGACXVRLDHEXKY-WXRXAMBDSA-N |
Chemical Details | |
|---|---|
| Formal Charge | 0 |
| Atom Count | 44 |
| Chiral Atom Count | 2 |
| Bond Count | 47 |
| Aromatic Bond Count | 11 |
Drug Info: DrugBank
| DrugBank ID | DB15439 |
|---|---|
| Name | Navoximod |
| Groups | investigational |
| Description | Navoximod is under investigation in clinical trial NCT02048709 (Indoleamine 2,3-Dioxygenase (IDO) Inhibitor in Advanced Solid Tumors). |
| Synonyms | Navoximod |
| Categories | Heterocyclic Compounds, Fused-Ring |
| CAS number | 1402837-78-8 |
Related Resource References
| Resource Name | Reference |
|---|---|
| CCDC/CSD | VOJXOK |
