DrugBank ID DB00281 Name Lidocaine Groups Description Ever since its discovery and availability for sale and use in the late 1940s, lidocaine has become an exceptionally commonly used medication [T583]. In particular, lidocaine's principal mode of action in acting as a local anesthetic that numbs the sensations of tissues means the agent is indicated for facilitating local anesthesia for a large variety of surgical procedures [F4349, L5930, L5948]. It ultimately elicits its numbing activity by blocking sodium channels so that the neurons of local tissues that have the medication applied on are transiently incapable of signaling the brain regarding sensations [F4349, L5930, L5948]. In doing so, however, it can block or decrease muscle contractile, resulting in effects like vasodilation, hypotension, and irregular heart rate, among others [F4349, L5930, L5948]. As a result, lidocaine is also considered a class Ib anti-arrhythmic agent [L5930, L5948, F4468]. Nevertheless, lidocaine's local anesthetic action sees its use in many medical situations or circumstances that may benefit from its action, including the treatment of premature ejaculation [A177625]. Regardless, lidocaine is currently available as a relatively non-expensive generic medication that is written for in millions of prescriptions internationally on a yearly basis. It is even included in the World Health Organization's List of Essential Medicines [L6055]. Synonyms Lidocaína alpha-diethylamino-2,6-dimethylacetanilide Lidocainum Lidocaina Lidocaine hydrochloride anhydrous
Lidocaine Lidocaine hydrochloride α-diethylamino-2,6-dimethylacetanilide Lignocaine 2-(Diethylamino)-N-(2,6-dimethylphenyl)acetamide 2-(Diethylamino)-2',6'-acetoxylidide more Brand Names Akten Lidocaine with Menthol Satohap Lidocaine 4% Pain Relieving Pad Numbify sanitize First Aid Antiseptic Rite Aid pharmacy
Lidocaine 2% and Epinephrine 1:50,000 Zims Max Freeze Duloxicaine Otizol HC Liq CBDMEDIC Itch and Rash First Aid Only Burn MLK F3 Kit Welly Superhero Supplies Kit INKED SCIENCE LIDOCAINE 4 Percent 4245 First Aid Kit Extra Strength Liquid Burn Relief Gel HealthWise Pain Relief Cream with Lidocaine Ultimate Lidocaine Pain Relief Patch First Aid Only First Aid/ Burn Lidocaine Hydrochloride Rapid Pain-relief Topical ReadySharp-A 4302 First Aid Kit TopCare Cold and Hot Pain Relieving Analgesic Afassco Burn Gel 4208 First Aid Kit Xryliderm lidoForte Hemorrhoidal Anecream 4110 First Aid Kit LidoWorx Performance Brands Steel Releaf Pain Relieving Liquid BENGAY Ginger Citrus Tough Love Pain Relieving Wound and Burn Care Refill Pack Lido-mp40 Priloheal Plus 30 Zims Lido Freeze 4318 First Aid Kit 4098 First Aid Kit Kit Large Office First Aid DermacinRx Lido V Pak Amino Rip Muscle Pain Relief Swift River Pain Relief CBD Clinic Pain Relief - Level 1 First Aid Research Bacitraycin Plus Maximum 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1000 Dr. Scholl's Cracked Heel Relief Cream Lidocaine 4% Gel Patch 4202 First Aid Kit Premjact Male Desensitizer Pound International BLUE ACME SLEEVE FIRST AID Contains 1000 PIECES FIRST AID Contains 404 PIECES 4199 First Aid Kit 4284 First Aid Kit Blue Tube 4266 First Aid Kit MyDerm Zilactin-L 4252 First Aid Kit Warrior Pain Relief Roll-On Maximum Strength POWERECT Lidocaine Male Delay 4102 First Aid Kit Panama Jack Burn Relief Gel Lipsorex Plus GoodSense Burn Relief Gel Family Medic First Aid Treatment - Liq Menthocin Patch with Lidocaine 4243 First Aid Kit CVS Health Lidocaine Plus Pain Relieving 4342 First Aid Kit Band-aid Brand Antiseptic Wash Lidocanna DermacinRx Lexifen Budpak First Aid 4171 First Aid Kit Nervive Pain Relieving Cream 4212 First Aid Kit OKeeffes Healthy Feet Pain Relief Cream Lidosite 25 Person ANSI Aramark Blood Clotting NOpioid-LMC Maximum Strength Pain Relief Lidocaine Patch Super T 4349 First Aid Kit Laryng O Jet Kit Lidocaine Hydrochloride Solution Lidocaine Hydrochloride and Dextrose Lidocaine Hydrochloride Gel CBD pain cream Fluocinolone Acetonide 0.025% / Lidocaine HCl Monohydrate 1% Icy Hot with Lidocaine Numstick Xylocaine 1% W Epinephrine 1:100000 Truu Balance Pain Relief Reg Rite Aid Rectal Care Syren Intimate Pain Relief Aspercreme Lidocaine Foot (Diabetic) 4044 First Aid Kit Xylocaine Dental Lidocaine HCl 2% and Epinephrine 1:100,000 Pain Relief Well at Walgreens 4103 First Aid Kit Aflexeryl-LC 50 Person ANSI Multi-Specialty Kit 4218 First Aid Kit LidoPatch Pain Relief Naturally HL Extra Strength Numbing Dyural 80 Kit Tattoo Numbing Cream Medi-Quik First Aid Antiseptic Meijer Odor Free Analgesic Pain Relieving Topical Analgesic 4032 First Aid Kit Ocean Breeze Pain Relief 4267 First Aid Kit DAYMARK FAK-35 First Aid Mega Patch Odynia-U Aprizio Pak 4190 First Aid Kit Triderma Pain Relief Medi-patch With Lidocaine Rx DOCTORS TOUCH Erase The Pain Lidocaine 4050 First Aid Kit Extra Strength First Aid Dentsply 2% Lidocaine With Epinephrine 1:50,000 4219 First Aid Kit Sunburn Pain Reliever CVS CBD MIST Topical Anesthetic PharmapureRx Menthotral Toplast Pain Relief Lidocaine 4percent plus Menthol 1percent Neptune Ice Precaine Painless Tattoo 2 Mueller First Aid Antiseptic 4378 First Aid Kit After Sun Burn Relief Lidocaine Continuous Spray DermacinRx Cinlone-II CPI Extra Strength Numbify Anorectal Lid O Creme Roll On Sx1 Medicated Post-Operative System Extra Strength Liquid Numbing Gel Curacaine D-Care 100X Alocane Severe Sunburn Satohap Lidocaine 4% Menthol 1% Pain Relieving Cream CBDaF Topical Gel DyNAmic Kit Walgreen Pain Relieving Fragrance Free Numb Skin Extra Strength Sunburn Relief Aspercreme Lidocaine No-Mess plus Lavender Medi-derm / L With Lidocaine LP Lite PAK Burn Ease, 3.5g Band-Aid Brand Hurt-Free Antiseptic Pain Relieving Lido-RX 4.1 Lidocaine 5% Spinal Anesthesia Tray 1% ARC FIRST AID Contains 404 PIECES Caring Mills Relief Patch with Lidocaine VIVA Patch CBD PAIN RELIEF Cream XeroBurn Burn Gel 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First Aid Kit Derma Gel Relief Xylocaine 0.5% W Epinephrine 1:100000 BLT Skin Cream 3-Step First Aid Kit Quality Choice Pain Relief 4% Lidocaine Cream Frost Lidocaine with Aloe Good Neighbor Pharmacy Aloe Vera Auebliss 4260 First Aid Kit CVS All Purpose First Aid Kit Pain Reliveing Patch Lidozen Marlido 25 Kit Aspercreme Medi-patch With Lidocaine Duane Reade Aloe Vera Pain Relieving 4197 First Aid Kit TheraCare 4% Lidocaine and 1% Menthol Cream 4312 First Aid Kit Viadur Xylocaine 5% Spinal Hemorrhoid Relief Cream ARC FIRST AID Contains 101 PIECES Pain Relief Rite Aid Regenecare Hydrogel Relief Gel Blood Clotting First Aid Dyural 40 Kit Xylocaine Oral Spray DermaRad Relief Pain Relief Patches Extra Strength Liquid Hemorrhoid Relief Gel curacaine Transdermal Corporation RECOVERY Numbing Auto 157 Genuine First Aid Burn Antiseptic Pain Relief With Aloe 4206 First Aid Kit Extra Strength Skin repair Ez Pain Relieving Numbing Label Kope Pain relief gel 4191 First Aid Kit After Bite Wipe Omeza Lavage FIRST AID Contains 101 PIECES Xylocaine Mpf Alivio Anestafoam Ana-Lex Burn Cream DCH Numbing Relief 4291 First Aid Kit Walgreens Cool n heat Lidocaine 4% Cream Numb 520 Xylocaine with epinephrine KY Duration for Men Lidocaine Hydrochloride Injection USP Lidocaine Pain Relieving 4372 First Aid Kit Healerz for Noses 4104 First Aid Kit Lidocaine Hydrochloride and Epinephrine Injection USP Walgreen Maximum strength pain relieving cleansing ProStat Blood Clotting First Aid LidoER Leva Set with Occlusive Dressing Lidocort Salonpas LIDOCAINE PLUS Senstend EQUATE Sunburn relief with Aloe After Sun Extra Strength Liquid Insect Bite Relief Gel Lidocaine 5% Topical Anorectal Cream LidoCream 10 Lidotor Fast Freeze Lidocaine Fruit of the Earth Sun Town City Aloe Vera After Sun with Lidocaine HCL Alcoholada Gel Pain Relieving Pain Numb Mentholix Lidocaine Hydrochloride and 5% Dextrose Injection USP Hustle Helper Comfort Enhancing Anesthetic Antimicrobial Wash Zingo 3 Step First Aid Kit Polyderm Antibiotic Ointment Salonpas Pain Relieving Cream Gold Bond Medicated Pain and Itch Relief 4250 First Aid Kit LenzaGel Lidoderm 5 Antibiotic Cream Plus Pain Relief for Kids BAKERS BEST Pain Relief with Pure Hemp Seed Oil eLenza Patch LidoSport Pain Relief Spinal Anaesthesia Tray Lidothol Walgreens Hemorrhoidal Pain Relief Amour CBD Meijer Pain Relieving Max Strength with Lavender Essential Oil Analgesic Watkins Burn Cream Baciguent Plus Pain Reliever Ont Lidonexe Extra Strength AfterTAT Slime more Indication Lidocaine is an anesthetic of the amide group indicated for production of local or regional anesthesia by infiltration techniques such as percutaneous injection and intravenous regional anesthesia by peripheral nerve block techniques such as brachial plexus and intercostal and by central neural techniques such as lumbar and caudal epidural blocks [F4349, L5930]. Categories Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use Agents that reduce seizure threshold Amides Amines Analgesics and Anesthetics
Anesthetics Anesthetics for Topical Use Anesthetics, Local Anilides Aniline Compounds Antiarrhythmic agents Antiarrhythmics, Class I Antiarrhythmics, Class Ib Antipruritics and Local Anesthetics Antipruritics, Incl. Antihistamines, Anesthetics, Etc. Cardiac Therapy Cardiovascular Agents Central Nervous System Agents Central Nervous System Depressants Cytochrome P-450 CYP1A2 Inhibitors Cytochrome P-450 CYP1A2 Inhibitors (moderate) Cytochrome P-450 CYP1A2 Substrates Cytochrome P-450 CYP2A6 Substrates Cytochrome P-450 CYP2B6 Substrates Cytochrome P-450 CYP2C18 Substrates Cytochrome P-450 CYP2C8 Substrates Cytochrome P-450 CYP2C9 Substrates Cytochrome P-450 CYP2D6 Inhibitors Cytochrome P-450 CYP2D6 Inhibitors (strength unknown) Cytochrome P-450 CYP2D6 Substrates Cytochrome P-450 CYP3A Substrates Cytochrome P-450 CYP3A4 Substrates Cytochrome P-450 CYP3A5 Substrates Cytochrome P-450 CYP3A7 Substrates Cytochrome P-450 Enzyme Inhibitors Cytochrome P-450 Substrates Dermatologicals Local Anesthesia Local Anesthetics (Amide) Membrane Transport Modulators Methemoglobinemia Associated Agents Nervous System Neuraxial Anesthetics Ophthalmologicals Otologicals P-glycoprotein inhibitors Peripheral Nervous System Agents Sensory System Agents Sodium Channel Blockers Throat Preparations Vasoprotectives Voltage-Gated Sodium Channel Blockers more ATC-Code S01HA07 D04AB01 R02AD02 C01BB01 S02DA01
N01BB52 C05AD01 N01BB02 more CAS number 137-58-6