NE8
6-AMINO-4-(2-PHENYLETHYL)-1,7-DIHYDRO-8H-IMIDAZO[4,5-G]QUINAZOLIN-8-ONE
Find entries where: NE8
is present as a standalone ligand in 4 entries
Chemical Component Summary | |
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Name | 6-AMINO-4-(2-PHENYLETHYL)-1,7-DIHYDRO-8H-IMIDAZO[4,5-G]QUINAZOLIN-8-ONE |
Identifiers | 6-amino-4-phenethyl-1,7-dihydropyrimido[6,5-f]benzimidazol-8-one |
Formula | C17 H15 N5 O |
Molecular Weight | 305.334 |
Type | NON-POLYMER |
Isomeric SMILES | c1ccc(cc1)CCc2c3c(cc4c2N=C(NC4=O)N)[nH]cn3 |
InChI | InChI=1S/C17H15N5O/c18-17-21-14-11(7-6-10-4-2-1-3-5-10)15-13(19-9-20-15)8-12(14)16(23)22-17/h1-5,8-9H,6-7H2,(H,19,20)(H3,18,21,22,23) |
InChIKey | PBZAIUVFRISTSZ-UHFFFAOYSA-N |
Chemical Details | |
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Formal Charge | 0 |
Atom Count | 38 |
Chiral Atom Count | 0 |
Bond Count | 41 |
Aromatic Bond Count | 21 |
Drug Info: DrugBank
DrugBank ID | DB08267 |
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Name | 6-amino-4-(2-phenylethyl)-1,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one |
Groups | experimental |
Description | 6-amino-4-(2-phenylethyl)-1,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one is a solid. This compound belongs to the stilbenes. These are organic compounds containing a 1,2-diphenylethylene moiety. Stilbenes (C6-C2-C6) are derived from the common phenylpropene (C6-C3) skeleton building block. The introduction of one or more hydroxyl groups to a phenyl ring lead to stilbenoids. It is known to target queuine tRNA-ribosyltransferase. |
Synonyms | 6-amino-4-(2-phenylethyl)-1,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one |
Drug Targets
Name | Target Sequence | Pharmacological Action | Actions |
---|---|---|---|
Queuine tRNA-ribosyltransferase | MVEATAQETDRPRFSFSIAAREGKARTGTIEMKRGVIRTPAFMPVGTAAT... | unknown |
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison
T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS.
Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682
Related Resource References
Resource Name | Reference |
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PubChem | 5326928, 135438475 |