NEC

N-ETHYL-5'-CARBOXAMIDO ADENOSINE

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is present as a standalone ligand in 9 entries

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Chemical Component Summary
Name	N-ETHYL-5'-CARBOXAMIDO ADENOSINE
Identifiers	(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-N-ethyl-3,4-dihydroxy-oxolane-2-carboxamide
Formula	C₁₂ H₁₆ N₆ O₄
Molecular Weight	308.293
Type	NON-POLYMER
Isomeric SMILES	CCNC(=O)[C@@H]1[C@H]([C@H]([C@@H](O1)n2cnc3c2ncnc3N)O)O
InChI	InChI=1S/C12H16N6O4/c1-2-14-11(21)8-6(19)7(20)12(22-8)18-4-17-5-9(13)15-3-16-10(5)18/h3-4,6-8,12,19-20H,2H2,1H3,(H,14,21)(H2,13,15,16)/t6-,7+,8-,12+/m0/s1
InChIKey	JADDQZYHOWSFJD-FLNNQWSLSA-N

Chemical Details
Formal Charge	0
Atom Count	38
Chiral Atom Count	4
Bond Count	40
Aromatic Bond Count	10

Drug Info: DrugBank

DrugBank ID	DB03719
Name	N-Ethyl-5'-Carboxamido Adenosine
Groups	experimental
Description	A stable adenosine A1 and A2 receptor agonist. Experimentally, it inhibits cAMP and cGMP phosphodiesterase activity. [PubChem]
Synonyms	N-Ethyl-5'-Carboxamido Adenosine

Drug Targets

Name	Target Sequence	Pharmacological Action	Actions
Endoplasmin	MRALWVLGLCCVLLTFGSVRADDEVDVDGTVEEDLGKSREGSRTDDEVVQ...	unknown

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682