NM7

2-(carbamoylamino)-5-(4-fluorophenyl)thiophene-3-carboxamide


Toggle HydrogenToggle Labels

Chemical Component Summary

Name2-(carbamoylamino)-5-(4-fluorophenyl)thiophene-3-carboxamide
Identifiers2-(aminocarbonylamino)-5-(4-fluorophenyl)thiophene-3-carboxamide
FormulaC12 H10 F N3 O2 S
Molecular Weight279.29
TypeNON-POLYMER
Isomeric SMILESc1cc(ccc1c2cc(c(s2)NC(=O)N)C(=O)N)F
InChIInChI=1S/C12H10FN3O2S/c13-7-3-1-6(2-4-7)9-5-8(10(14)17)11(19-9)16-12(15)18/h1-5H,(H2,14,17)(H3,15,16,18)
InChIKeySAYGKHKXGCPTLX-UHFFFAOYSA-N

Chemical Details

Formal Charge0
Atom Count29
Chiral Atom Count0
Bond Count30
Aromatic Bond Count12

Drug Info: DrugBank

DrugBank IDDB17058 
NameTPCA-1
Groups investigational
DescriptionTPCA-1 is a selective inhibitor of human IκB kinase 2 (IKK-2).[A253152]
Synonyms
  • 3-thiophenecarboxamide, 2-((aminocarbonyl)amino)-5-(4-fluorophenyl)-
  • TPCA-1
  • 2-((aminocarbonyl)amino)-5-(4-fluorophenyl)-3-thiophenecarboxamide
  • Ikk 2 inhibitor iv
  • Ikk-2 inhibitor iv
Categories
  • Enzyme Inhibitors
  • Protein Kinase Inhibitors
  • Sulfur Compounds
CAS number507475-17-4

Related Resource References

Resource NameReference
Pharos CHEMBL257167
PubChem 9903786
ChEMBL CHEMBL257167
ChEBI CHEBI:91403