DrugBank ID DB00420 Name Promazine Groups Description A phenothiazine with actions similar to chlorpromazine but with less antipsychotic activity. It is primarily used in short-term treatment of disturbed behavior and as an antiemetic. It is currently not approved for use in the United States. Synonyms Promazina Promazinum Promazine hydrochloride Promazin 10-(3-(Dimethylamino)propyl)phenothiazine
N,N-dimethyl-3-(10H-phenothiazin-10-yl)-propan-1-amine N-Dimethylamino-1-methylethyl thiodiphenylamine N-(3-Dimethylaminopropyl)phenothiazine Promazine more Brand Names Promazine HCl Inj 50mg/ml Indication Used as an adjunct for short term treatment of moderate and severe psychomotor agitation. Also used to treat agitation or restlessness in the elderly. Categories Adrenergic alpha-1 Receptor Antagonists Adrenergic alpha-Antagonists Adrenergic Antagonists Agents producing tachycardia Agents that produce hypertension
Amino Acids Amino Acids, Branched-Chain Amino Acids, Peptides, and Proteins Anticholinergic Agents Antidepressive Agents Antiemetics Antipsychotic Agents Antipsychotic Agents (First Generation [Typical]) Autonomic Agents Central Nervous System Agents Central Nervous System Depressants Cytochrome P-450 CYP1A2 Inhibitors Cytochrome P-450 CYP1A2 Inhibitors (strength unknown) Cytochrome P-450 CYP1A2 Substrates Cytochrome P-450 CYP2C19 Substrates Cytochrome P-450 CYP2C9 Substrates Cytochrome P-450 CYP2D6 Substrates Cytochrome P-450 CYP3A Substrates Cytochrome P-450 CYP3A4 Substrates Cytochrome P-450 Enzyme Inhibitors Cytochrome P-450 Substrates Dopamine Agents Dopamine Antagonists Dopamine D2 Receptor Antagonists Gastrointestinal Agents Heterocyclic Compounds, Fused-Ring Histamine Antagonists Histamine H1 Antagonists Moderate Risk QTc-Prolonging Agents Muscarinic Antagonists Nervous System Neurotoxic agents Neurotransmitter Agents Peripheral Nervous System Agents Phenothiazines Phenothiazines With Aliphatic Side-Chain Psycholeptics Psychotropic Drugs QTc Prolonging Agents Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome Serotonin 5-HT2 Receptor Antagonists Serotonin 5-HT2A Receptor Antagonists Serotonin 5-HT2C Receptor Antagonists Serotonin Agents Serotonin Receptor Antagonists Sulfur Compounds Tranquilizing Agents more ATC-Code N05AA03 CAS number 58-40-2 
