RDF/PRD_000638

PHOSPHORAMIDON

RDF/PRD_000638 is described in the Biologically Interesting Molecule Reference Dictionary (BIRD).

The representative PDB ID is 1TLP.

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Chemical Component Summary

NamePHOSPHORAMIDON
SynonymsPHOSPHORAMIDON
Identifiers(2S)-2-[[(2S)-2-[[hydroxy-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyl-oxan-2-yl]oxy-phosphoryl]amino]-4-methyl-pentanoyl]amino]-3-(1H-indol-3-yl)propanoic acid
FormulaC23 H34 N3 O10 P
Molecular Weight543.504
TypePEPTIDE-LIKE
Isomeric SMILESC[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)O[P@](=O)(N[C@@H](CC(C)C)C(=O)N[C@@H](Cc2c[nH]c3c2cccc3)C(=O)O)O)O)O)O
InChIInChI=1S/C23H34N3O10P/c1-11(2)8-16(26-37(33,34)36-23-20(29)19(28)18(27)12(3)35-23)21(30)25-17(22(31)32)9-13-10-24-15-7-5-4-6-14(13)15/h4-7,10-12,16-20,23-24,27-29H,8-9H2,1-3H3,(H,25,30)(H,31,32)(H2,26,33,34)/t12-,16-,17-,18-,19+,20+,23-/m0/s1
InChIKeyZPHBZEQOLSRPAK-XLCYBJAPSA-N
CompositionPolymer Sequences: RHA-LEU-TRP
BIRD classENZYME INHIBITOR
Represented AsSINGLE MOLECULE
Compound Detailsn/a
Descriptionn/a

Chemical Details

Formal Charge0
Atom Count71
Chiral Atom Count8
Bond Count73
Aromatic Bond Count10

Drug Info: DrugBank

DrugBank IDDB02557 
NamePhosphoramidon
Groups experimental
Synonyms
  • Phosphoramidon
  • Phosphoramidon disodium
Categories
  • Amino Acids, Peptides, and Proteins
  • Anti-Infective Agents
  • Carbohydrates
  • Enzyme Inhibitors
  • Glycoconjugates
CAS number36357-77-4

Drug Targets

NameTarget SequencePharmacological ActionActions
Kell blood group glycoproteinMEGGDQSEEEPRERSQAGGMGTLWSQESTPEERLPVEGSRPWAVARRVLT...unknown
NeprilysinMGKSESQMDITDINTPKPKKKQRWTPLEISLSVLVLLLTIIAVTMIALYA...unknowninhibitor
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682

Related Resource References

Resource NameReference
Pharos CHEMBL479579
PubChem 445114
ChEMBL CHEMBL479579
ChEBI CHEBI:45353