TE4

Tetracaine

Find entries where: TE4

is present as a standalone ligand in 6 entries

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Chemical Component Summary
Name	Tetracaine
Synonyms	2-(dimethylamino)ethyl 4-(butylamino)benzoate
Identifiers	2-(dimethylamino)ethyl 4-(butylamino)benzoate
Formula	C₁₅ H₂₄ N₂ O₂
Molecular Weight	264.363
Type	NON-POLYMER
Isomeric SMILES	CCCCNc1ccc(cc1)C(=O)OCCN(C)C
InChI	InChI=1S/C15H24N2O2/c1-4-5-10-16-14-8-6-13(7-9-14)15(18)19-12-11-17(2)3/h6-9,16H,4-5,10-12H2,1-3H3
InChIKey	GKCBAIGFKIBETG-UHFFFAOYSA-N

Chemical Details
Formal Charge	0
Atom Count	43
Chiral Atom Count	0
Bond Count	43
Aromatic Bond Count	6

Drug Info: DrugBank

DrugBank ID	DB09085
Name	Tetracaine
Groups	vet_approved approved
Description	Tetracaine is an ester local anaesthetic currently available in combination with lidocaine as a cream and patch.
Synonyms	Tetracaine hydrochloride 2-(dimethylamino)ethyl 4-(butylamino)benzoate Tetracaína Tetracaine HCl Amethocaine 2-(Dimethylamino)ethyl p-(butylamino)benzoate Metraspray Medihaler-Tetracaine p-Butylaminobenzoyl-2-dimethylaminoethanol Tétracaïne p-(butylamino)benzoic acid β-(dimethylamino)ethyl ester Dicaine Amethocaine HCl Diäthylaminoäthanol ester der p-butylaminobenzösäure Tetracaine
Brand Names	Ametop Gel 4% Eclipse Topical Analgesic LL Blue Gel Anesthetic Denti-care Topical Anesthetic Gel Panocaine Gel Lidocaine and Tetracaine Pliaglis Tetracaine2 Sj3 FranklyNumb 3 Penichillin Pain Prescriptives Topical Analgesic LL Exactacain Topical Anesthetic T.R.U.E. Test Thin-Layer Rapid Use Patch Test Pro Plus Zap Topical Anesthetic Spray Aerosol Denti-Care Denti-Freeze Topical Anesthetic Raspberry One Touch Advanced Topical Anesthetic Gel Cool Mint Ritual Tattoo Burn Solution Cream Niphanoid Benzocaine 20% / Lidocaine 10% / Tetracaine 10% Supracaine Aem 754mg/65gm One Touch Topical Anesthetic Gel Spinal Anesthesia Tray Denti-Care Denti-Freeze Topical Anesthetic Strawberry Kovanaze Denti-Care Denti-Freeze Topical Anesthetic Bubblegum Blt 3 Synera Zap Topical Anesthetic Gel TetraVisc Forte Pontocaine Dps 0.5% Supracaine Aerosol 11.6mg/gm tetraVIV Advanced Cold Sore Care TetraVisc One Touch Advanced Topical Anesthetic Strawberry Ice Cetacaine Spray Burn Cream BLT Skin Cream Henry Schein Topical Anesthetic Gel Pontocaine 5 mg/ml Zap Liquid Denti-care Topical Anesthetic Liquid Spray Endospray Zap Topical Anesthetic Spray Denti-Care Denti-Freeze Topical Anesthetic Cherry Blockaid Spinal Anaesthesia Tray Cetacaine Topical Anesthetic Minims Tetracaine Hydrochloride Numfast Tetracaine Green NeuroMed LA Altacaine Super T Cetacaine Anesthetic Painless Tattoo 3 Inderma MD Ritual Tattoo Reveal Foam Plush anesthetics T NeuroMed Topical Analgesic LA Cetacaine Liquid One Touch Advanced Topical Anesthetic Cherry Tetracaine HCL Ndc 72934- 5010-4 Benzocaine 20% / Lidocaine 8% / Tetracaine 4%. Lidocaine 7% / Tetracaine 7% Denticare Pro-freeze One Touch Advanced Topical Anesthetic Bubble Gum Tetracaine Comfortox Tetracaine Lidocaine 23% / Tetracaine 7% Cutiecaine Pontocaine Pws Inj 20mg/amp Viractin Gel Tetracaine Hydrochloride Dermacaine-R Denti-Care Denti-Freeze Topical Anesthetic Mint Tetramex Tetracaine (Base) Viractin Moisturizing Cream Tetragel Punch Topical Analgesic Pontocaine
Indication	Ophthalmic tetracaine is indicated for the for procedures requiring a rapid and short- acting topical ophthalmic anesthetic. The combination lidocaine and tetracaine patch is indicated for local dermal analgesia for superficial dermatological procedures and superficial venous access. The combination lidocaine and tetracaine cream is intended to provide topical local analgesia for superficial dermatological procedures.
Categories	Acids, Carbocyclic Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use Aminobenzoates Anesthetics Anesthetics for Topical Use Anesthetics, General Anesthetics, Local Antipruritics and Local Anesthetics Antipruritics, Incl. Antihistamines, Anesthetics, Etc. Benzene Derivatives Benzoates Central Nervous System Agents Central Nervous System Depressants Dental Agents Dermatologicals Esters of Aminobenzoic Acid Local Anesthesia Local Anesthetics (Ester) Methemoglobinemia Associated Agents Nervous System Ophthalmologicals para-Aminobenzoates Peripheral Nervous System Agents Sensory Organs Sensory System Agents Vasoprotectives
ATC-Code	C05AD02 N01BA03 D04AB06 N01BA53 S01HA03
CAS number	94-24-6

Drug Targets

Name	Target Sequence	Pharmacological Action	Actions
Ryanodine receptor 1	MGDAEGEDEVQFLRTDDEVVLQCSATVLKEQLKLCLAAEGFGNRLCFLEP...	unknown	modulator
Ryanodine receptor 2	MADGGEGEDEIQFLRTDDEVVLQCTATIHKEQQKLCLAAEGFGNRLCFLE...	unknown	modulator
Voltage-gated sodium channel alpha subunit	MEQTVLVPPGPDSFNFFTRESLAAIERRIAEEKAKNPKPDKKDDDENGPK...	unknown	blocker

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682