TPA

TRANS-2-PHENYLCYCLOPROPYLAMINE


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Chemical Component Summary

NameTRANS-2-PHENYLCYCLOPROPYLAMINE
Identifiers[(1S,2R)-2-phenylcyclopropyl]azanium
FormulaC9 H12 N
Molecular Weight134.198
TypeNON-POLYMER
Isomeric SMILESc1ccc(cc1)[C@H]2C[C@@H]2[NH3+]
InChIInChI=1S/C9H11N/c10-9-6-8(9)7-4-2-1-3-5-7/h1-5,8-9H,6,10H2/p+1/t8-,9+/m1/s1
InChIKeyAELCINSCMGFISI-BDAKNGLRSA-O

Chemical Details

Formal Charge1
Atom Count22
Chiral Atom Count2
Bond Count23
Aromatic Bond Count6

Drug Info: DrugBank

DrugBank IDDB02665 
Name(1R,2S)-2-Phenylcyclopropanaminium
Groups experimental
DescriptionA propylamine formed from the cyclization of the side chain of amphetamine. This monoamine oxidase inhibitor is effective in the treatment of major depression, dysthymic disorder, and atypical depression. It also is useful in panic and phobic disorders. (From AMA Drug Evaluations Annual, 1994, p311)
Synonyms
  • (1R,2S)-tranylcypromine(1+)
  • (1R,2S)-2-Phenylcyclopropanaminium
CAS number1986-47-6

Drug Targets

NameTarget SequencePharmacological ActionActions
Trypsin-1MNPLLILTFVAAALAAPFDDDDKIVGGYNCEENSVPYQVSLNSGYHFCGG...unknown
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682

Related Resource References

Resource NameReference
PubChem 448753
ChEBI CHEBI:131520