TPQ

5-(2-CARBOXY-2-AMINOETHYL)-2-HYDROXY-1,4-BENZOQUINONE


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Chemical Component Summary

Name5-(2-CARBOXY-2-AMINOETHYL)-2-HYDROXY-1,4-BENZOQUINONE
Synonyms5-(2-CARBOXY-2-AMINOETHYL)-4-HYDROXY-1,2-BENZOQUINONE; 2,4,5-TRIHYDROXYPHENYLALANINE QUINONE; TOPA QUINONE
Identifiers(2S)-2-amino-3-(4-hydroxy-3,6-dioxo-1-cyclohexa-1,4-dienyl)propanoic acid
FormulaC9 H9 N O5
Molecular Weight211.171
TypeL-PEPTIDE LINKING
Isomeric SMILESC1=C(C(=O)C=C(C1=O)O)C[C@@H](C(=O)O)N
InChIInChI=1S/C9H9NO5/c10-5(9(14)15)1-4-2-7(12)8(13)3-6(4)11/h2-3,5,13H,1,10H2,(H,14,15)/t5-/m0/s1
InChIKeyAGMJSPIGDFKRRO-YFKPBYRVSA-N

Chemical Details

Formal Charge0
Atom Count24
Chiral Atom Count1
Bond Count24
Aromatic Bond Count0

Drug Info: DrugBank

DrugBank IDDB04334 
Name6-hydroxydopa quinone
Groups experimental
Synonyms
  • 6-Hydroxyphenylalanine-3,4-dione
  • (S)-α-amino-4-hydroxy-3,6-dioxo-1,4-cyclohexadiene-1-propanoic acid
  • 6-hydroxydopa quinone
  • L-topaquinone
  • Topa quinone
Categories
  • Amines
  • Amino Acids
  • Amino Acids, Aromatic
  • Amino Acids, Cyclic
  • Amino Acids, Peptides, and Proteins
CAS number64192-68-3

Drug Targets

NameTarget SequencePharmacological ActionActions
Membrane primary amine oxidaseMNQKTILVLLILAVITIFALVCVLLVGRGGDGGEPSQLPHCPSVSPSAQP...unknown
Primary amine oxidaseMGSPSLYSARKTTLALAVALSFAWQAPVFAHGGEAHMVPMDKTLKEFGAD...unknown
Phenylethylamine oxidaseMTPSTIQTASPFRLASAGEISEVQGILRTAGLLGPEKRIAYLGVLDPARG...unknown
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682