Pyridoxine is the 4-methanol form of vitamin B6, an important water-soluble vitamin that is naturally present in many foods. As its classification as a vitamin implies, Vitamin B6 (and pyridoxine) are essential nutrients required for normal functioning of many biological systems within the body. While many plants and microorganisms are able to synthesize pyridoxine through endogenous biological processes, animals must obtain it through their diet. More specifically, pyridoxine is converted to pyridoxal 5-phosphate in the body, which is an important coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, and aminolevulinic acid. It's important to note that Vitamin B6 is the collective term for a group of three related compounds, pyridoxine, pyridoxal, and pyridoxamine, and their phosphorylated derivatives, pyridoxine 5'-phosphate, pyridoxal 5'-phosphate and pyridoxamine 5'-phosphate. Although all six of these compounds should technically be referred to as vitamin B6, the term vitamin B6 is commonly used interchangeably with just one of them, pyridoxine [A32836]. Vitamin B6, principally in its biologically active coenzyme form pyridoxal 5'-phosphate, is involved in a wide range of biochemical reactions, including the metabolism of amino acids and glycogen, the synthesis of nucleic acids, hemogloblin, sphingomyelin and other sphingolipids, and the synthesis of the neurotransmitters serotonin, dopamine, norepinephrine and gamma-aminobutyric acid (GABA) [A32837]. Pyridoxine is used medically for the treatment of vitamin B6 deficiency and for the prophylaxis of isoniazid-induced peripheral neuropathy (due to [DB00951]'s mechanism of action which competitively inhibits the action of pyridoxine in the above-mentioned metabolic functions). It is also used in combination with [DB00366] (as the commercially available product Diclectin) for the treatment of nausea and vomiting in pregnancy.
Synonyms
Piridoxina
Pyridoxol
3-hydroxy-4,5-bis(hydroxymethyl)-2-methylpyridine
Pyridoxine hydrochloride
Pyridoxine
Vitamin B6
Pyridoxinum
3-hydroxy-4,5-dimethylol-α-picoline
5-hydroxy-6-methyl-3,4-pyridinedimethanol
2-methyl-3-hydroxy-4,5-dihydroxymethylpyridine
Brand Names
Nutra Boost
Multi-phyto Capsules
TL-Care DHA
B6 Cap 100mg
Ellis Tonic
Davimet with Fluoride
American Eagle Energizer Plus Vitamin Supplement Drink
Levomefolate Calcium, Cyanocobalamin and Pyridoxine Hydrochloride
Children's Chewable Vit and Min Tab
Multi Vitamin, Iron and Fluoride
Stress Formula B-comp + 500mg Vit C Tab
Folica-V
Carthaphy Cap
EC + Complex
Vitamin B6 Tab 100mg USP
Dynam Ampoule Et Tablet
Tini-cal Ampoules
Bacmin
PRENATE Restore
Doxylamine succinate and Pyridoxine hydrochloride
Children's Chewable Multivitamin Complete With Minerals
Multivitamines Pour Enfants (chewable Tablets)
Se-Natal
Nexa Plus
Flintstones Multiple Vitamins Tab
OB Complete Prenatal
Perioe lucky fresh - cavity care
Vitranol
Vitamin B6 & B12 With Folic Acid
Multra With Iron
Lipovite
Homosismin
Tobakient
Tricare Prenatal Quick Dissolve
Kanga-kid Multi-vitamin & Mineral
B6 Plus Tab
Mycelized Childrens Multi-vitamin Liq
Chewable Multiple Vitamins Plus Extra C
Deriton
Senior Multi One
Floriva
B-plex
M.V.I.-12
Prenate DHA
Flexadyn Tab
MultiVitamin with Fluoride
Flinstones Multiple Plus Iron
B Complex Tablets
Vitamin B6 250 Mg Capsules
B Complex W C and B12 Inj
Twin G.F. Powder Vanilla Flavor
Docosavit
Vitafant
Obstetrix DHA Combo Pack
healthy mamaBE WELL ROUNDED BE WELL ROUNDED
Hemocyte Plus
Children's Chewable Multi Vit W Iron
Vitamin B Compound W C Tab 500mg
Zatean-Pn Plus
Pre-Tabs DHA Prenatal Multi-vitamin/Mineral Supplement with DHA/EPA
Vc II
CitraNatal Essence
Taliva
Teva-doxylamine/pyridoxine Dr
Maintain Multiple Vitamin & Minerals
Multiple Vit Plus Iron Tab
Prenatal
Iron Vitamins B6,b12,c,folic Acid Tab
B50 B Complex Tab
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Childrens Multiple Vit and Min Chew Tab
Isotamine B 300
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Tandem Plus
Multiple Vitamins Plus Iron Tab
Oncovite
Prenatal Vitamins and Minerals Tablets
Vitamin B-6 50 Mg Tablet
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WellFola
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Swiss One
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B Complex With C 300mg Tab
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Vp-ggr-B6
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PreNatal 19
Mini-B Tab
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Marnatal F
Supravite Stress Avec Vit E Cuivre Et Zinc
Molyhen
Obstetrix EC
B-complex Tab
Wellness Formula
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Harvest Of Values All B Complex Tab
Prenatvite Complete
Poly-Vi-Flor with Iron
Extra-Virt Plus DHA
B50 Complex
Vit B6 Tab 250mg
Virt-Pn DHA
Totalvit Plus
Floriva Plus
B Complex 50 Vitamin Cap
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Zoo Chews Plus Iron
Vit B Complex Plus Vit C 550mg
Iron, Vit & Min Supp
Natelle One
Vitamin B6 Tablets-250mg
Fortamines 10 Capsules
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Alkadrenergy Tablets
Diclectin
RediChew
Stress B & C Caplet
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Phytofortis + Calcium A-D
Leritone Junior
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Kaydia Patch
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BP Vit 3
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SetonET
Dr.Pauhls TOOTHPAST E LIME MANDARIN FLAVOR
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Only One - Tablet
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Magnum-75 Vitamin and Mineral Supplement
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24 Multivitamins + Minerals
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Kenwood Liquid Supplement
B6 Pyridoxine HCl Tab 50mg
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Taron-C DHA
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Children's Chewable Multiple Vitamins - Tab
Escavite Lq
Thrivite Rx
Prenatal Vitamin and Mineral Supplement Tab
BumP DHA
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Pyridoxine-S Tab 50mg
Foltabs 800
Maxi 10 Tab
Vitafol Plus
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Recal D
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Vitamine B6 Tab 250mg
NeuroBion
Z-mass PM Vitamin and Mineral Supplement
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Q.T. #4 Vitamin and Mineral Dietary Supplement
Relnate DHA
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B-Serene Rx
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Nutrilite Double X
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Vitamin B Compound W Vit C 250mg Tab
Vitamin B-6 200mg
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For Kids Only Chewable Multivitamins
Select-OB Plus DHA Prenatal Supplement Plus DHA
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MultiVitamin, Iron and Fluoride Drops
Mega Balance
PreGen DHA
Vitamin B Complex W C 300mg Tab
Children's Chewable Multiple Vitamins With Iron Tablets (chewable Tablets)
Multiple Vitamins - Tablet
Tricare Prenatal DHA One With Folate
Vitamines Et Mineraux Enfants 970
WestGel DHA
Anaplex Tab
Vitamin B-6 Tab 200mg
50 Plus Multiple Vitamins & Minerals
Corvita
TL Gard Rx
Multi Tabs
Animi-3 with Vitamin D
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Prenate Mini
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Vitamin B-6 100mg
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Somarexin and C 1000
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Medi Wrinkle Serum
Livita Children
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Niacex B6
Nexa Select Rx Prenatal Vitamin with Plant-Based DHA
Childrens Chewable Vitamins
B C Antistress Cap
Keylosa
Twin Ultra Liquid Grape Flavor
RE Prenatal Multivitamin with Iron
Vinate Care
Multivitamin with 1.0 mg Fluoride
B-50 Hi Potency B Vitamins Tab
Phytoplex B Liq
Florafol Pediatric 0.25 mg/mL Multivitamin and Fluoride Liquid Drops
Swiss One Timed Release Tab
Prenatal Vi-min
Fusion Plus
Prenate Chewable
Cda-21 Vitamins With Non-medicinal Probiotic Complex
Multi-Vitamin Drops with Fluoride and Iron
Shen Min Vitamin Supplement
Vitamine 110 Liq
hormaSAN forte
Formula Cm
NESTABS Prenatal Multi-vitamin/Mineral Supplement
Envirocomplex
Stress B-complex Plus Iron With Vitamins C&e
Virt-Pn
Sun-rype Vitaburst
Duet DHA 400
NicAzelFORTE
Folet DHA
Vitamin B6 100mg
Formula Cn
Geritol Liquid
Se-Care Chewable
Multivitamin & Minerals (iron Free)
C-B Complex
Virt-Nate
Rocky Mountain Multiple Vit and Min Mega Tab
NataFort
Complete Mega B
Childrens Chewable Multiple Vitamins Tab
Lubricant Eye Drops
Cedevita Plus Vitamin Supplement
B-100 Hi Potency B Vitamins Tab
PROTECT IRON Liquid
Premium Prenatal
Diacomp - Cap
Multivitamine
Master Key Multi Vitamin Multi Mineral Formula 2
Dr.Pauhls TOOTHPAST E PATCHOULI MUSK FLAVOR
Pnv-dha
Vitamin B6 Cap 250mg
Corvite Free
Niva-Fol
Ifb
Vitaphil DHA
Folivane-Plus with Ascorbic Acid Precursors
Multivitamins W Iron
Neo-bex
Vitrexyl plus Iron
B-complex Tablets
Multivitamins and Minerals for Young Men
PreferaOB
Multivitamins and Multiminerals Formula Regular Tablet
Garfield Chewable Multivits Plus Iron Tab
Neomultivite
Dialyvite
Super Klb6 Tab 17mg
Multi Vitamines - Liq
Vitasure
Doctor's Choice Brand for Men
Inatal Advance
Pregvit Folic 4
Revitex Ampoules Et Comprimes
Neonatal19
Pro Hers Vanilla
Meth-X Vitamin and Mineral Supplement
Lip - Fac Formula
Stress B Capsules With Vitamin C
Quflora Pediatric Drops
Supravite C 1000
Vitamine Du Groupe B Plus Fer - Liq
Vitamin B Complex Suppl
Vita Balance 2000
Cell Power Boosting Essence
Multivitamins for Children
Vtb Vitamin and Mineral Supplement
Multitabs
Re Ob 90 DHA
Trinatal Ultra
Swiss Total One
Pyridoxine Hydrochloride Injection USP 100 mg/ml
Daily Balance Tab
Lipotropic Ctr
Pnv-OB-dha
Cavan X
Vitamin B6 100 mg
B Complex Plus C 300mg Tab
Pyridoxen Tab 50mg
Vinate AZ
Low Potency B Complex Tab
Revival 1 Tab
Formula O-care Vitamin and Mineral Supplement
Homosistrox Capsules
B6 Tab 100mg
Poly-Vite/Iron Oral Solution
Reliv So Sense Daily Vitamin Supplement
FolaMax
Vitafol Caplet
Kidmag Vitamins W Magnesium Tab
Megavites Tab
Pyridoxine HCl Inj 100mg/ml
Children's Chewable With Iron
Earthpals Children's Chewables Multi-vitamin & Mineral Tablets
Obtrex One
Bugs Bunny Chew Multi Vit Plus Iron
Vitramyn
Swical-energy-2
H.W. Children's Chewable Multi Vit & Mineral
Pregvit Folic 5
Gestamine Comprimes
Kanga-kid Vitamins & Iron
Multi Enfants Tab
Timed Release Vita-vim Srt
B6 100mg Pyridoxine HCl
Ventrixyl
Great Day/am Formula Tab
Tri Adrenopan
Vitamin B Complex + C 600mg Tab
Formula Lf
TL-Fluorivite
L-Methyl-MC
Multivitamins and Minerals - Complete
Se-Tan PLUS
Powertech Vitamin and Mineral Supplement
Mega-vim 75 With Beta-carotene - Tablets
Prost-10 Vitamin and Mineral Supplement
Vitamin B Complex W C Tab
Av-VITE FB
Stress B With 1000 Mg Vitamin C
Children Choice Multivit Chewable Tab
B Complex With C 550mg
ProFola
Multi Plex II - Tab
B-complex With Vitamin C, Biotin, Folic Acid
Virt-Care One
Irospan 24/6
Multivitamines Et Mineraux Junior Regulier
Strovite One Caplets
KeyFolic
Swiss One Multi Vit & Chel Min Tab
Virt-Vite Forte
Maxine Vitamin and Mineral Supplement
Megavite Rx
Isotonix Advanced B-complex Vitamins With Potassium and Magnesium
Nata Komplete
Nephrocaps-QT
B-Nexa
Baisix
Daily Supplement Packs
Balanced B-complex Vit + Vit C&e Tab
Multi Pro
Prenatal Plus Vitamins
FaBB
B Complex 500 Tab
Childrens Chewable Multivitamins
Natal-V RX Multi-vitamin/Multi-mineral
PNV-Select
VITAFOL Gummies
Children's Chewable Multi Vitamins
Virt-Bal DHA Plus
Escavite D
PRENATE Enhance
Lipo-B-C Tab
WesNatal DHA Complete
Stress Complex 600 Avec Vit E Cuivre Zinc
Vol-Plus
Jenliva
Iberet 500
Se-Care Conceive
Multi-vitamin Dietary Supplement
Prenatvite Plus
B-plex 100
Calcium PNV
Vp-CH-pnv
PreNatal Vitamins Plus
Multiple Vitamins and Minerals Tab
Complex-75
ahoSAN
Focalgin B
Tricare Prenatal
Moms Choice Rx
Vitamin B Complex 100
Nephrocaps
C-force
Antlerviron
UltimateCare ONE
Zintrexyl-C
V & M Vitamin and Mineral Supplement
Women's Formula
Neo-bex Injectable
Vp-pnv-dha
Multi Vitamin Drops with Fluoride and Iron
CitraNatal Harmony
B-complex
Multi-Vit-Flor
Vitamin B-Complex
Multra Plex
Stress Formula Tab
Amerix Multivitamin
PureVit DualFe Plus
P.N. Vitamin-mineral Drink
RenaPlex-D
M-Natal Plus
B Totum 500
Multi Vitamin and Fluoride
Reaphirm Plant Source DHA
B-complex 50
Vitamin B6 200mg
Vitamine B6 Tab 25mg USP Chewable
Fem - Pmt
Hemarexin Tab
B6 400mg Ctr Tab
Children's Chewable Multivitamins and Minerals
Supravite 10ml Ampoule
Stress Formula
Multi Vitamins & Minerals
Multiple Vitamins With Iron
Cavan Folate OB
Vita-B-75 Cap
Folcaps Omega-3
Supplement De Multivitamines Infusion Arome Fruits Rouges
Pnv-VP-U
Munit-E Tablet
Vitamin B Compound Tab
Multivit with Fluoride
Lipo Factors Plus B6
Xvite
Prenate Elite
Reebok
Udamin Sp
Vitazyme
Folic-K
Swiss One Multivitamin and Mineral Caplet
Nephron FA
Palm Springs Multvit and Min Tab
Vitrexyl
B-50 Complex
Advanced AM PM
Formula Adr-vitamin B2,b6 W Calpan Tab
Tonicol Et A-D-C Ampoules/comprimes
Super-pote Vitamin Supplement
Formula D.S.
Dialyvite 5000
Lgb-dtx Tab 10mg
Efferlife Multivitamins and Minerals
Multiple Vitamins Tab
Elite OB Prenatal Multivitamin
Multivitamins
Folivane-PRx DHA
Ultimate Tab
Vitamin B6 100mg Tab
Multi-Vitamin Fluoride Drops
Novel Vita
Folet One
Select OB
Sopalamine/3b Plus C
B-6 Pyridoxine HCL
TL-Folate
Osteo Formula
Pyridoxine
Folcaps
Multiple Vitamins Plus Iron for Women
Lipovitan
Mega 13 Multivitamin Formula
Min-chex Cap
Vitamin B6 100 Mg USP
Children's Vitamins W Iron Chewable
Klb6 Tablets 17mg
Zingiber
Genicin Vita-Q
vitaMedMD Rx Plus
Ultra Enerforce
Premel
Vitamine B6 100 Mg - Tablet
Vol-Care Rx
Z Bec Tab
Fusion Activator Formula Tab
Prenatal Vitamins Plus
Allbee C 800 Tab
Neonatal DHA
Orange Flavored Crystal Chews Tab
Balanced B100
Genicin Vita-S
Dr.Pauhls TOOTHPAST E VANILLE BLACK TEA FLAVOR
Natalvirt 90dha
B-complex 100
Concept OB
Vita-doxine Cap 250mg
PNV-First
Integra Plus
Solaray
B-Combo
C. Vit-min Formula
Lustime Angel
WesCap-C-DHA
Lutime
NESTABS ABC Prenatal Multi-vitamin/Mineral Supplement with DHA/EPA
Methaver
Concept DHA
Lorid
Formula Pro-B
Osteoshield
Stress Tablets
Luna Vitamin and Mineral Bar for Women
Se-Natal One
Kmg Plus
Z-force Vitamin and Mineral Supplement
Mangadyn
L Fac Tab
Multivitamins and Minerals Tablets
Mvc 9 Plus 3 Inj
Advanced B & T Formula
Doxylamine Succinate and Pyridoxine Hydrochloride
Multivitamin with 0.25 mg Fluoride
Childrens Chewable Vitamin Tab
Forty Plus Vitamin Supplement
Allbee With C 550 Cap
Vitamin B6 Tab 100mg
Surbex-500 With Zinc
Men's Biomultiple Vitamin and Mineral Supplement
Iron 25mg With Vit B-cmplx, Vit C, Cu & Mo
Mnps Formula Supplement
Provida DHA
Folika-V
Niaacinamide Azelaic AC TURMER FA B6 Zinc Ox Copper
Quflora Pediatric
Formula Js
Essential B Tablets
Floradix Formula Liq
Energy 80 Prolonged Release Tab
Vitaflex Dietary Suplement
Fibrik
L.I.P. Complex
Taron BC
Calcium Folic Acid Plus D Chewable
New Chapter's D'adamo 4 Your Type Multiple for Type O
Tri-Zel
Vitalife - Capsule
Hylazinc
Multi 1000
Adult Formula 50+
B 6 Plus
Carbassist Tablets
Corvita 150
Nicaprin
Ni-C-E-LE Plus
Chewable Multiple Vitamins Tab
Mvc
M.V.I. 12
PureFe Plus
Multi-Vit with Fluoride and Iron
Multi-Vitamin Fluoride
Hi Potency B52 B Complex Tab
Vit B6 Pyridoxine HCl Tab 50mg USP
Cavan Heme OB
Total Living Concepts Formula One - Tab
Multivitamins and Minerals for Young Women
NicAzel Doxy Kit
Virt-PN DHA
Everyday Multiple Vitamins With Iron
Pro Pcos Citrus
Supravite Bouteille 250ml
Pyridoxine Hydrochloride
Multi Vitamin - Mineral
Florafol FE Pediatric 0.25 mg/mL Multivitamin and Fluoride Liquid Drops
Balanced B-100 B-complex Vitamins Tab
Dialyvite 3000
Revit Plus Cap
Nestabs ONE
Vyo Cylate - Pwr
Childrens Chewable Multiple Vitamins W.iron
PrePLUS
M.V.I. Pediatric
Vitamin B6 Capsules 100mg
Zatean-Pn
Pyridoxine Hydrochloride Injection, USP
Quflora FE
B Compound 50mg Tab
natelle COMPLETE
Insur-all Vitamin Supplement
Vasula Tab
B Complex W Vit C W Non-med Yeast&liver Tab
Zinc Plus Vitamins C & B6 Lozenges
Se-Tan DHA
Cataplex F Tab 2mg
Indication
Pyridoxine is indicated for the treatment of vitamin B6 deficiency and for the prophylaxis of [DB00951]-induced peripheral neuropathy. It is also approved by Health Canada for the treatment of nausea and vomiting in pregnancy in a combination product with [DB00366] (as the commercially available product Diclectin).
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison
T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS.
Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682