VAL

VALINE

Find entries where: VAL

is present as a standalone ligand in 48 entries

as a non-polymer is covalently linked to polymer or other heterogen groups 68 entries

is present in a polymer sequence 220,839 entries

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Chemical Component Summary
Name	VALINE
Identifiers	(2S)-2-amino-3-methyl-butanoic acid
Formula	C₅ H₁₁ N O₂
Molecular Weight	117.146
Type	L-PEPTIDE LINKING
Isomeric SMILES	CC(C)[C@@H](C(=O)O)N
InChI	InChI=1S/C5H11NO2/c1-3(2)4(6)5(7)8/h3-4H,6H2,1-2H3,(H,7,8)/t4-/m0/s1
InChIKey	KZSNJWFQEVHDMF-BYPYZUCNSA-N

Chemical Details
Formal Charge	0
Atom Count	19
Chiral Atom Count	1
Bond Count	18
Aromatic Bond Count	0

Drug Info: DrugBank

DrugBank ID	DB00161
Name	Valine
Groups	approved nutraceutical
Description	Valine is a branched-chain essential amino acid that has stimulant activity. It promotes muscle growth and tissue repair. It is a precursor in the penicillin biosynthetic pathway.
Synonyms	L-alpha-Amino-beta-methylbutyric acid (2S)-2-Amino-3-methylbutanoic acid 2-Amino-3-methylbutyric acid L-valine (S)-Valine L-valin Val Valine L-(+)-alpha-Aminoisovaleric acid
Brand Names	4.25% Travasol Amino Acid Injection With Electrolytes In 10% Dextrose Premasol - sulfite-free (Amino Acid) Aminosyn-PF 10% FreAmine III Travasol E Renamin (amino Acids) Injection 5% Travasol Amino Acid Injection Without Electrolytes In 20% Dextrose ProcalAmine 2.5% Travasol Amino Acid Injection Without Electrolytes In 10% Dextrose Quickmix Aminosyn Sulfite Free Travasol 2.5% Travasol Amino Acid Injection With Electrolytes In 10% Dextrose Olimel 3.3% E Aminosyn RF Injection Clinisol Primene 10%-liq IV 4.25% Travasol Amino Acid Injection With Electrolytes In 5% Dextrose Quickmix Aminosyn II with Electrolytes Smofkabiven Vamin N Smofkabiven Extra Nitrogen Electrolyte Free 4.25%trav. Amino Acid InJ.W.O.elect.5%dext. Periolimel 2.5% E 2.5%travasol Amino Acid InJ.W.eleC.W.25%dex Plenamine Aminosyn 5% RenAmin 2.5% Travasol Amino Acid Injection With Electrolytes In 10% Dextrose Clinimix 2.75% Travasol Amino Acid Injection With Electrolytes In 25% Dextrose Quickmix Primene 10% Novamine Aminosyn II 7% M In 10% Dextrose(dual Chamber) Perikabiven Olimel 5.7% E 2.75% Travasol Amino Acid Injection With Electrolytes In 5% Dextrose Quickmix 2.75%travasol Amino Acid InJ.W.eleC.W.5%dex. Aminosyn RF Essepna 4.25% Travasol Amino Acid Injection Without Electrlytes In 10% Dextrose 5% Travasol Amino Acid Injection Without Electrolytes In 25% Dextrose 4.25% Travasol Amino Acid Injection With Electrolytes In 25% Dextrose Aminosyn 10% W Electrolytes Aminosyn Aminosyn II 5% Inj Olimel 4.4% Aminosyn II Aminosyn II in Dextrose HepatAmine Aminosyn II 7% With 10% Dextrose 4.25% Travasol Amino Acid Injection Without Electrolytes In 20% Dextrose Quick Mix 2.5% Travasol Aa With Electrolytes With 25% Dextrose Injec Travasol Amino Acid Inj 8.5% 8.5% Freamine III 4.25% Travasol Amino Acid Injection With Electrolytes In 20% Dextrose Quickmix Smofkabiven Peripheral Aminosyn 7% Travasol Amino Acid Inj 5.5% 4.25% Travasol Amino Acid Injection With Electrolytes In 20% Dextrose Aminosyn II 8.5% Injection Clinimix 2.5% Travasol Aa Without Electrolytes In 10% Dextrose Injec Olimel 4.4% E Olimel 5.7% Nephramine Liq IV 2.75% Travas. Amino Acid InJ.W.elecw.25%dex Synthamin Aminosyn 8.5% BranchAmin Vamin 18 Electrolyte-free Smofkabiven Extra Nitrogen 4.25% Travasol Amino Acid Without Electrolytes In 5% Dextrose Quickmix Aminosyn II 8.5% With 50% Dextrose Nutrineal Pd4 Aminosyn II with Electrolytes in Dextrose with Calcium Aminosyn II In Dextrose Injection Aminosyn II 8.5% M In 20% Dextrose (dual Chamber) Primene Smofkabiven Electrolyte Free Aminosyn HF 4.25% Amino Acid Injection Without Electrolytes In 20% Dextrose Quickmix Bcaa 4% Inj Kabiven Travasol Inj Without Electrolytes 8.5% 20% Prosol Hepatasol Travasol Inj Without Electrolytes 5.5% Aminosyn-PF Aminosyn II and Dextrose Aminosyn 3.5% M ProSol NephrAmine Aminosyn II 7% Injection Clinimix FreAmine HBC Aminosyn 8.5% Injection With Electrolytes Aminosyn II 7% With 50% Dextrose Aminosyn II 10% With Electrolytes 5% Travasol Amino Acid Injection With Electrolytes In 20% Dextrose Aminosyn-PF 7% Clinimix E TrophAmine Olimel 7.6% Olimel 7.6% E 4.25% Travasol Amino Acid Injection Without Electrolytes In 25% Dextrose 4.25%travasol Amino Acid InJ.W.elecw.5%dex.
Indication	Promotes mental vigor, muscle coordination, and calm emotions. May also be of use in a minority of patients with hepatic encephalopathy and in some with phenylketonuria.
Categories	Amino Acids Amino Acids, Branched-Chain Amino Acids, Essential Amino Acids, Peptides, and Proteins Dietary Supplements Proteinogenic Amino Acids Supplements
CAS number	72-18-4

Drug Targets

Name	Target Sequence	Pharmacological Action	Actions
Propionyl-CoA carboxylase beta chain, mitochondrial	MAAALRVAAVGARLSVLASGLRAAVRSLCSQATSVNERIENKRRTALLGG...	unknown
Branched-chain-amino-acid aminotransferase, cytosolic	MKDCSNGCSAECTGEGGSKEVVGTFKAKDLIVTPATILKEKPDPNNLVFG...	unknown
Valine--tRNA ligase	MSTLYVSPHPDAFPSLRALIAARYGEAGEGPGWGGAHPRICLQPPPTSRT...	unknown
Valine--tRNA ligase	MSTLYVSPHPDAFPSLRALIAARYGEAGEGPGWGGAHPRICLQPPPTSRT...	unknown	substrate
Propionyl-CoA carboxylase beta chain, mitochondrial	MAAALRVAAVGARLSVLASGLRAAVRSLCSQATSVNERIENKRRTALLGG...	unknown	substrate
Branched-chain-amino-acid aminotransferase, cytosolic	MKDCSNGCSAECTGEGGSKEVVGTFKAKDLIVTPATILKEKPDPNNLVFG...	unknown	substrate
Monocarboxylate transporter 10	MVLSQEEPDSARGTSEAQPLGPAPTGAAPPPGPGPSDSPEAAVEKVEVEL...	unknown	inhibitor
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Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682

Related Resource References

Resource Name	Reference
PubChem	6971018, 88733505, 6287
ChEMBL	CHEMBL43068
ChEBI	CHEBI:16414, CHEBI:57762
CCDC/CSD	FIYWIW, VALHCL12, ROKBOI02, LUDHAT, HOSMAE, WIHQUA, VALEHC11, OXEMEL, AHEJEC01, AHEJEC03, FACXUD, SONCED, VALHCL11, BANPOW, AHEJEC, BERPET, HOTXIY, VALIDL05, AHEJEC02, ABEHOF, NUZMIG, OPEFUL, UHEPIG, TUZJIJ, QURSUR, FITMEA, EWOZIZ, RUXWIQ, VALNIT01, HAGYEU, PAHCIL, GUQJUZ, DLVALC, ROKBOI, VALEHC10, OCOLID, MAZBOI, MAZBIC
COD	2203771, 2202036

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.

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VAL

VALINE

Chemical Component Summary

Chemical Details

Drug Info: DrugBank

Drug Targets

Related Resource References