VIB

3-(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-5-(2-HYDROXY-ETHYL)-4-METHYL-THIAZOL-3-IUM

Created:	2001-04-17
Last modified:	2020-01-26

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Chemical Details
Formal Charge	1
Atom Count	35
Chiral Atom Count	0
Bond Count	36
Aromatic Bond Count	11

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Chemical Component Summary
Name	3-(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-5-(2-HYDROXY-ETHYL)-4-METHYL-THIAZOL-3-IUM
Synonyms	THIAMIN; VITAMIN B1
Systematic Name (OpenEye OEToolkits)	2-[3-[(4-amino-2-methyl-pyrimidin-5-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]ethanol
Formula	C₁₂ H₁₇ N₄ O S
Molecular Weight	265.355
Type	NON-POLYMER

Chemical Descriptors
Type	Program	Version	Descriptor
SMILES	ACDLabs	10.04	n1c(c(cnc1C)C[n+]2c(c(sc2)CCO)C)N
SMILES	CACTVS	3.341	Cc1ncc(C[n+]2csc(CCO)c2C)c(N)n1
SMILES	OpenEye OEToolkits	1.5.0	Cc1c(sc[n+]1Cc2cnc(nc2N)C)CCO
Canonical SMILES	CACTVS	3.341	Cc1ncc(C[n+]2csc(CCO)c2C)c(N)n1
Canonical SMILES	OpenEye OEToolkits	1.5.0	Cc1c(sc[n+]1Cc2cnc(nc2N)C)CCO
InChI	InChI	1.03	InChI=1S/C12H17N4OS/c1-8-11(3-4-17)18-7-16(8)6-10-5-14-9(2)15-12(10)13/h5,7,17H,3-4,6H2,1-2H3,(H2,13,14,15)/q+1
InChIKey	InChI	1.03	JZRWCGZRTZMZEH-UHFFFAOYSA-N

Drug Info: DrugBank

DrugBank ID	DB00152
Name	Thiamine
Groups	vet_approved approved investigational nutraceutical
Description	Thiamine or thiamin, also known as vitamin B1, is a colorless compound with the chemical formula C12H17N4OS. It is soluble in water and insoluble in alcohol. Thiamine decomposes if heated. Thiamine was first discovered by Umetaro Suzuki in Japan when researching how rice bran cured patients of Beriberi. Thiamine plays a key role in intracellular glucose metabolism and it is thought that thiamine inhibits the effect of glucose and insulin on arterial smooth muscle cell proliferation. Thiamine plays an important role in helping the body convert carbohydrates and fat into energy. It is essential for normal growth and development and helps to maintain proper functioning of the heart and the nervous and digestive systems. Thiamine cannot be stored in the body; however, once absorbed, the vitamin is concentrated in muscle tissue.
Synonyms	Tiamina thiaminium Thiamine thiamine(1+) Aneurin Thiamine hydrochloride Antiberiberi factor thiamine(1+) ion Thiaminum Vitamin B1 Thiamine chloride Thiamine mononitrate Thiamin
Brand Names	Derma-force Neonatal Vitamin Deriton Childrens Chewab Vitamin W Chel Minerals Multiple Vitamins Escavite D Multivitamin with 0.25 mg Fluoride One A Day Tab Se-Natal One Balanced B-100 B-complex Vitamins Tab Active OB Children's Multivitamins Vitaday Tab Children's Chewable Tab Multi #2 Multivitamins and Minerals Tablets Cal M Tab DuetDHA Complete Prenatal Vitamin and Mineral Supplement Quflora FE Tricare Prenatal DHA One With Folate Nutrifer Plus Tablets Childrens Chewable Multiple Vitamins W.iron B Complex With C 300mg Tab B Compound 50mg Tab Pretrate Neo Bex Elixir Children's Chewable With Iron PNV-First Pnv Ob DHA Hemocyte Plus Renal Caps Dialysis/Stress Vitamin Supplement tensioSAN Folic-K Vitamines Et Mineraux Comprimes Beminal With C Fortis Pws Duet DHA Balanced Lipovite Paramettes Adults Mvc 9+4 Inj Vitamin B-1 100 Mg Tablets Children's Chewable Multivitamins With Minerals Beminal 500 Tab Vita-vim - Tab Betaxin Liq 100mg/ml One A Day Multiple Vit W Minerals NovaFerrum Multivitamin with Iron Pediatric Drops B Complex 25mg Vitamin Supplement Childrens Chewable Multiple Vitamins Tab 50 Plus Multi 1000 Kids Stuff With Iron Tablets Multivitamins and Multiminerals Formula Regular Tablet PM Caps Twin Ultra Liquid Lemon-lime Flavor Tandem Plus Century Complete Paramettes Multivits Plus Iron Tab (teens) Chewable Multiple Vitamins Tab Multiple Vitamin Tab Pnv-VP-U OB Complete Prenatal Irospan 24/6 Prefera OB plus DHA Hypo Vites Tab Tendera-OB Timed Release B-complex 100 Multi Vitamins & Minerals Multi Nt-OX Taron-C DHA Everyday Multiple Vitamins With Iron B-100 Caps THIAMINE HYDROCHLORIDE injection, solution Se-Natal 19 Chewable Abavite Prenatal Vi-min Prenatol-M Multi-Vitamin With Fluoride FloraFol M.V.I. Adult Croq-vit Pour Enfants Folika-NC Vitamin B-1 Thiamine HCl 100mg Vimeral Tab Biovim Tab Ferra Naka Plus Vitamins Nutri-Tab OB Somavit Brand Vitamins and Minerals Complex Phytofortis + Calcium A-D Multra With Iron Virt Vite GT Folika-T Thiamine Hydrochloride Injection, USP Doctor's Choice Brand for Men Mvc 9 Plus 3 Inj Neonatal Plus Vitamin B Complex 500 Tab Formula Fm Vitamins & Minerals Tab Multi Vitamin with Fluoride B-complex-50 Tab Materna Multivitamines Plus Fer Pour Enfants (chewable Tablets) Multivitamines Pour Enfants (chewable Tablets) MVC-Fluoride RE Nata OB Vitrexyl Formula B Virt-Bal DHA Plus B Virol Formula O.C. Multi Enfants Tab Livita Children Balanced B50 Complex Neo-bex Multi Vitamin Plus Iron Folet DHA B-plex 100 Surbex-500 With Iron Inatal Advance Gesticare DHA Insur-all Vitamin Supplement Manganese 50mg Plus B1 & E Tab Acti-MN + B1 + C Caplet Keylosa Mangadyn Tricare Prenatal Stress Tab With Zinc, Copper and Vitamin E Swical-energy 3e Age TriStart DHA Vitamin B1 Extra Once A Day PR Natal 400 ec Childrens Chewable Multivitamins W Iron Vol-Care Rx PrePLUS Children's Chewable Multi Vit W Iron Multi-actin NataFort Toni Com Liq Myhephron Dialysis and Stress Supplement TL-Folate Jenliva Iron, Vit & Min Supp Prenatal Vitamins and Minerals Tablets Revit Tab Multiple Vitamins Childrens Chewable Folika-V Multi-Vitamin Fluoride Drops Multivitamines Et Mineraux Junior Regulier B-100 Vitamin Supplement Prenatal Vitamin and Mineral Supplement Tab Revit Plus Cap Ultimate OB DHA Totalvit Plus Edge OB Pregnancy Multivitamin Folic 5 L-Methyl PNV DHA Childrens Chewable Vitamins W Iron Prenatal Supplement - Tab Sopalamine/3b Tab Synergistic Manganese Cap Triveen-Duo DHA Super Vita Vim Multivitamins and Minerals Stress Formula Glyco Plus Ect ahoSAN Orange Flavored Crystal Chews Tab Mega Capsules AzesChew Nitro Vites - Tab Vege 1 Daily Tab Vita B Complex Tab Adult Formula 50+ Multi-kid B-50 Complex Tab Floravit - Syr Multi-Vitamin Fluoride and Iron Drops Chela Iron Plus C,b Complex P.N.P. Vitamin Drink Preplus Vitamin B1 100 mg Quflora FE Pediatric Drops Livron Plus Ampoule M.V.I.-12 Tonimol Cap Liq Appedrine Multivitamins and Minerals for Women Pregnancy Multivitamin Stress Complex 600 Avec Vit E Cuivre Zinc Multi-vitamins Genicin Vita-Q Virt-PN Complete Natal DHA Zalvit Trinatal Ultra Balanced B-50 B-complex Vitamins, Timed Rele Vitamin B Complex 100 Tab Maltlevol Liq Multivitamins W Iron Innersource Tab CompleteNate Chewable Poly Vi Flor Chewable Tab Multiple Vitamins Plus Iron - Tab Virt-Advance Megavites Tab Nutra-clear Forty Plus Vitamin Supplement Meplex T 750 Ply Vi Sol Chewable Tab Vc II Vitamin B Compound Tab Revitalize Multi-vitamin and Mineral Complex Dialyvite with Zinc Trinatal GT Chewable Children's Complete Multivitamins With Essential Minerals Balanced B-complex Vit + Vit C&e Tab Childrens Chewable Vitamins Natural Source Spectrum With Beta Carotene MultiVitamin, Iron and Fluoride Drops Phytopure Mycelized Childrens Multi-vitamin Liq Polymine Avec Zinc Et Cuivre Vtb Vitamin and Mineral Supplement Venexa Neo-bex Injectable For Kids Only Chewable Multivit. Plus Iron Pregvit Thiamine HCl Inj 100mg/ml Vita-worth B-complex Tablets Complete Multivitamins and Minerals for Children Vit B Complex Ctr Liqui Infant Vitamins Spectrum Performa Multivitamins and Minerals Tablets Stress B Complex With C,e, Zinc and Copper Bewon Elixir Vitamin B Complex Tab Thiamine HCl Tab 100mg Maintain Multiple Vitamin & Minerals WesCaps Children's Chewable Multiple Vitamins With Iron Tablets (chewable Tablets) For Kids Only Chewable Multivitamins - Tab Multivitamins and Minerals - Complete Dermamed Nutrition for troubled skin Penta-thion Pwr Multi-Vit with Fluoride Multi Tabs Chew.multiple Vits.with Extra C for Children Master Key Multi Vitamin Multi Mineral Formula 2 Chewable Adult Multivitamins With Minerals Multiple Vitamins - Tablet Chewable Multiple Vitamins Plus Iron Tab Dexifol Prometa Twin Ultra Liquid Fruit Punch Flavor Formula Pro-B Balanced B 125 Srt CitraNatal Essence Complete One A Day Tab Children's Vitamins Chewable B-1 Caps 500mg B-plus - Tab Dothelle DHA Children Choice Multivit Chewable Tab Corvite Z Bec Tab Choice OB DHA Tricare Prenatal Compleat Floradix Formula Liq Nutra Boost One-A-day Advance Men's Complete Multivitamins and Minerals Tablets Timed Release Super Stress Mega B Plus 1000mg Vit C Tab Great Day/am Formula Tab Prenara Fortamines-10 Comprimes Provida OB Thiamine Hydrochloride Injection USP, 100mg/ml Vitafol-OB Plus DHA Prenatal Supplement Plus DHA Multivitamine Escavite Lq Vitamin B-Complex Viva Kids - Tab Supravite Bouteille 250ml VitaPhil Aide Children's Multivitamins With Iron Extra P.N. Vitamin-mineral Drink Mix Maltlevol 12 Liq RE Prenatal Multivitamin with Iron Vitamin B1 Tab 100mg USP FolaGent DHA Multivitamins and Minerals for Young Men Prenate Elite Mega-vim 75 With Beta-carotene - Tablets Relnate DHA Vitafol Plus PreNatal Vitamins Plus Multi - N.T.O.x Formula - Tab TL-Care DHA Diaplex Dia-vite Neo Vites Tab B-100 Complex Tablets Trinaz O-Cal FA multivitamin Vol-Plus Multra Plex Essential B Tablets Feminique W Iron and Calcium Tab Nephrocaps-QT Livron Plus Tab Ventrixyl Fe Vitaflex Dietary Suplement B Stress C + Iron & Vite Megavite Rx Glyco Lite Ect Childrens Chewable Multiple Vitamins Plus Fe Gestamine Comprimes Hemarexin Tab Liqui Vita Stress Formula B-comp + 500mg Vit C Tab Vitrexate FE Nata Komplete Right Choice A.M. Multi Formula - Caplet PNV-Select Reaphirm Plant Source DHA Vitamines Pour Bebes Et Enfants Natal PNV NESTABS ABC Prenatal Multi-vitamin/Mineral Supplement with DHA/EPA Multi B Multiple Vitamins and Minerals Tab Multivitamin with fluoride Vitabanks Vitamin Tab Vitrexate Zavitrol Super Multi Alsimine W Vitamins A D Allbee With Vitamin C Cap Complete One-A-day - Tab Dalivit Maxum Multi-vite NESTABS DHA Prenatal Multi-vitamin/Mineral Supplement with DHA/EPA vitaMedMD One Rx Duet DHA Stress Formula Vit B With C Complex Hill.vite Bal-Care DHA Folitin-Z Spectrum 2 Cap Multi Vitamin - Mineral PR Natal 430 Thiamine HCl Tab 50mg Children's Vitamins W Iron Chewable VIL-Rx Multi Rol Nutra-Z Stress B Capsules With Vitamin C O-Cal Prenatal Vitamin Super Vita-vim With Beta-carotene - Tab Multi Vitamin, Iron and Fluoride Vigem 12 Liquid Vitafol OB Caplet Davimet-M Hormodausse Plus Calc Et D Tab Stress B Complex With C, E and Iron Tab Magnum-75 Vitamin and Mineral Supplement Efferlife Multivitamins and Minerals Kaydia Patch Biovita Paire OB Plus DHA Omnivex Leritone Junior Multivit-liq Vitrexyl plus Iron Vit-HA Multi Vitamin and Zinc Supplement Neo-vites & Minerals Tab Complexe B-75 Multi Vitamin Drops with Fluoride and Iron Poly-Vi-Flor with Iron Viamon Ampoules Et Comprimes Classic Swiss One 10 Multivitamin and Mineral Tab Multi-Vitamin with Fluoride Vit B1 Ctr Srt 100mg Multi Vitamines - Liq Enrich Core Pack - Children Vitamin and Mineral Supplement Multivitamins and Minerals for Men Liqui B Complex Renate DHA P.N. 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Supplement Multi Vitamin & Minerals Allbee C 800 Tab Flintstones Multiple Vitamins Plus Iron bioJET Fusion Plus Vitamin B Complex W C 300mg Tab Vita Plex Tab Vitafol One Twin Ultra Liquid Orange Flavor Prenatal Plus Vitamins Advanced B & T Formula Maxi 10 Tab Paramettes Chewable Multivitamins Plus Iron Stress Ctr Srt Prenatal and Post Partum Supplement Multivit with Fluoride B Complex W C and B12 Inj Women's Biomultiple Vitamin and Mineral Supplement SetonET-EC Select-OB Plus DHA Prenatal Supplement Plus DHA Supravite Stress Avec Vit E Et Fer Virt-Nate Vitaphil 90 DHA Davimet with Iron Multiple Vitamins With Minerals Tablets Complex-75 Nutri-Tab OB plus DHA OB Complete DHA Phytoplex B Liq B Complex Tablets Multi-12 Pediatric Mini-B Tab Children's Chewable Multivitamin and Multimineral Stress B Complex With C and E Tab Multi-phyto Capsules Infuvite Pediatric Ultra Enerforce Vit B Complex Plus Vit C 550mg Children's Chewable Vit and Min Tab Floriva Plus Synergistic Manganese Capsules Davimet Kindervites Multi Plex II - Tab Iron 25mg With Vit B-cmplx, Vit C, Cu & Mo Lexazin NEONATAL Complete B-plex H.W. Children's Chewable Multi Vit & Mineral Kanga Sport Vitamins B & C Plus Minerals Daily Energy Brand B-complex Nutrol-B-complex Bal-Care DHA Essential Ribotin-E Vitranol Fe Nrg Plus Liq Multi Vite Liq Junior Lipotropic Ctr HemeNatal OB plus DHA Total Living Concepts Formula One - Tab Multi Vitamin and Fluoride Mega Balance Prenatal Multi-12/k1 Pediatric Davimet with Fluoride Bacmin Flintstones Multiple Vitamins Rocky Mountain Multiple Vit and Min Mega Tab Select OB Stress Formula Multivitamin Tablets USP Prena1 B Complex W Vitamin C Fortis Cap Hi Potency Multi Tab hormaSAN forte Everyday Multiple Vitamins Surbex 500 Filmtab C-Nate DHA Dynam Ampoule Et Tablet B6 Plus Tab Fibrik Gtf-vitamin-minerals & Pancreatin Tab Beminal W C Fortis Inj FolaMed DHA Prenatal, DHA Vita Day Tab Vitamin B Cpd W Vit C Tab N.E.U. Complex Bewon Elixir 0.05mg/ml Poly-VI-sol Drops Prenatrix Distilpure Msm V & M Vitamin and Mineral Supplement Multiple Vitamins Tab Amladex Multivit Et Fer Ampoules Et Comprimes Vitamin B + C Cap Corvite Free Maxine Vitamin and Mineral Supplement One Tablet Daily Mens Formula PNV Prenatal Plus Multivitamin Vita-amine Cap 100mg Multivitamin Thiamine VP-Vite Rx D'pantothenic Acid-B1-B2 Tab Numark Multivitamins Vitamin B1 Tab 2mg USP Body Rox B Complex 50 Vitamin Cap Poly-Vitamin with Fluoride Thiamine HCl 100mg W C 20mg Multiple Vitamins Plus Iron for Women Corvita Women's Change Formula Children's Chewable Multi Vitamins Isotonix Multitech Vitamin Mineral Supplemen Liquid B Complex 50 Potassium Plus Vit B Complex Xyzbac Childrens Multiple Vit and Min Chew Tab Nutrilite Double X Soluvit N Multivitamin with 1.0 mg Fluoride One A Day Advance Adults Enviroflex - Tab Marnatal F Junior Multi Vitamins - Regular Vital Be-100 Super Daily No 2 Vasula Tab Provida DHA Chela-manganese 50 Plus Poly-Vi-Flor Sibergin B - Cap Ziphex Formula Hh PreferaOB Card-floe II Tab B-complex Childrens Chewable Tab M.V.I. Paediatric Integra Plus Medi Msm (methyl Sulfonyl Methane) Dialyvite Supreme D Ultra Hr Multi 12 Injection Twin Opti Pwr Cc II Multitabs Puralor Daily Balance Tab Lorid T.R.I. B-plex Src Multi Plex I - Tab Milltrium Senior Vitamin and Mineral Supplement Twin G.F. Powder Vanilla Flavor G.A.S. Complex Paramettes Chewable Multivits With Iron Tab Prenatabs FA Prenatal Vitamin and Mineral Supplement -tab Cedevita Sugar-free Vitamin Supplement Cavan Alpha Natalvirt Ca Neonatal19 Hylazinc Swiss One Timed Release Tab Reno Caps Se-Natal Zatean-Pn Maxi 6 Liq PreQue 10 Multitam Cavan Heme OB Chromease Tab Multi-Vitamin Fluoride Garfield Chewable Multivits Plus Iron Tab High Potency Vitamin B Complex + C Tab K.L. Vitamin-mineral Materna-tab Wellness Formula Oncovite Sopalamine/3b Plus C Bev 29 Tab Tini-cal Ampoules Vita B + C 500 Tab Sopalamine 3b Plus Hemarexin Liquid and Drinkable Ampoules Orti B Poly-VI-flor Balanced B-50 Complex Prevital Tab NeuroBion INATAL Ultra Thrivite 19 Thiamine HCl Tab 25mg Vitafant B1 400mg Ctr Tab Tricare Prenatal DHA One Vitamin B Complex Suppl Virt Nate Folica-V PreferaOB plus DHA Florafol FE Pediatric 0.25 mg/mL Multivitamin and Fluoride Liquid Drops Renate Multi Pro B 50 Capsules M.V.I. 12 Iron Folate Plus Multi-force for Women Tab Tricare Prenatal Quick Dissolve HemeNatal OB Men's 50+ Multi Vite Liq Adult Cavan Prenatal Balanced B-100 Timed Release Kanga-V Multivitamins & Minerals Pro Hers Vanilla Vitafol Ultra Flinstones Multiple Plus Iron RE Nata Multi-Vit with Fluoride and Iron Se-Tan PLUS Premium Prenatal CitraNatal Assure C-B Complex Focalgin 90 DHA Nephrocaps Adeks - Dps Vitamin B Complex Folica BE Virt-Caps Timed Release B-complex 50 Prenatal Mega Antioxidant Multi-vitamins With Minerals Multiple Vitamins & Minerals Tablets Stress Formula Tab Vasodyn Tab Carbassist Tablets Virt-Nate DHA Twin Ultra Liquid Grape Flavor Children's Chew Multi & Min Tab Virt-Tabs Prenatal Plus Multivitamin Plus DHA MiniCaps Stress Vitamin B With C Complex Tablets Stresstabs + Zinc-copper Surbex-500 With Zinc TM-Vite RX Women's Formula Novel Vita Chewable Multiple Vitamins for Children Multivitamins One Daily VITES Prenatal Vitamins Plus Low Iron Quflora Pediatric Drops RenaPlex-D Supravite Pour Enfants Zyvit B-complex Tablets Garfield Chewable Multivitamins Tab Gynedyn Tab B Complex With C 300mg B Complex Plus C 300mg Tab Revival 1 Tab Supravite Stress Avec Vit E Cuivre Et Zinc Vyo Cylate - Pwr Kid's Choice Children's Chewable Vitamins - Tab Vasculine Prenate Star Dexivite Foltabs Prenatal Prenatvite Envirocomplex Thiamiject Injection - Liq Im IV 100mg/ml Stress Tablets OB Complete 400 Mega Plex III - Pck Multivitamines Multivitamins and Minerals for Young Women Florafol Pediatric 0.25 mg/mL Multivitamin and Fluoride Liquid Drops Prenatal Vitamins Plus Duet DHA 400 ec L.G.I.T. Super B Compound W 500mg Vit C Vitamine B1 Tab 100mg USP Gemvites Jr Tab Chewable Multiple Vitamins With Iron Multi Vitamin-mineral Formula Olympian Multi Vit Plus Minerals Tab Multi-vitamin Dietary Supplement Folivane-Plus with Ascorbic Acid Precursors Multiple Vitamin Plus Minerals Tab Q.T. Vitamin and Mineral Drink Mix Chewable Multivitamins Zoo Chews Plus Iron Dexatrim Tablets B-complex Tab Antlerviron Childrens Chewable Multiple Vitamins Vigo Multivitamins Drops/lozenge Chewable Multiple Vitamins Plus Extra C Children's Chewable Multivitamin Complete With Minerals Materna - Tab Thiamine HCl Injection - Liq 100mg/ml Protect Plus SO 60 C. Vit-min Formula Obstetrix EC Vital-D Rx MI-Vite RX Men's Multi Master Formula Alertonic Childrens Chewable Vitamin Tab Orifer F Azesco Centratex TriphroCaps Swiss Total One Tandem OB 24 Multivitamins + Minerals Only One - Tablet Multivitamins for Children Swiss One Multi Vit & Chel Min Tab Duet DHA 400 B-50 Hi Potency B Vitamins Tab Vita-vim With Beta-carotene - Tab MultiVitamin Drops with Fluoride and Iron Complex 5 - Pwr Revitex Ampoules Et Comprimes Palm Springs Multvit and Min Tab Vitamin B Compound With Vitamin C Fortis Capsule Dtc Multivitamin with Fluoride Low Potency B Complex Tab Se-Care Conceive Concept OB Strovite One Caplets Stress Tab Vita Balance 2000 Cavan Folate OB Super Vitalex Ampoule Buvable Vitamin B1 Tab 100mg Vp-heme Ob DHA Children Choice Multivitamin W Iron Chew Tab PNV Tabs 29-1 Opti-manganese + B1 + C Caplet B-50 Complex M-Natal Plus B Complex W C Forte Cap Vitamin B1 100mg Tablet Fizz Multivitamins for Kids W C Loz Fortaplex Inj PreGen DHA Prenatryl PureFe Plus Fem Time Tab Thiamine Hydrochloride Inj 100mg/ml PR Natal 430 ec Vita-Rx Diabetic Vitamin Children's Chewable Multi-vitamin VitaXyme Stress Formula + Iron Vitamines Et Mineraux For-2 Chewable Multivitamins Plus Iron PreTAB Sun-rype Vitaburst Bev B-150 Swical-energy-2 RE FAC-x Neonatal DHA Paramettes Syrup Prenatvite Complete PROTECT IRON Liquid Usana Megavitamin Tablets - Tab WestGel DHA Vitamin B Complex + C 300mg Cap Vitamin B Complex W C Tab PureFe OB Plus Stress Forte Plus Lipotropic Factors Super Charged Energy Twin G.F. Powder Virt-Vite Plus Kenwood Liquid Supplement Vitamin B Compound W C Tab 500mg Senior Multi One Zoo Chews Multi-11 Betaxin PNV Prenatal Vitamin B-complex 100 Hi Potency Stress B Tension With C Tender Age Multi Vitamins Vinate AZ Mvc Vitamin B1 100mg Se-Plete DHA Strovite Forte Caplet Alkadrenergy Tablets Super Kids Chewable Multivitamin Multimineral (chewable Tablets) WesCap-C-DHA Replavite Finazol Daily-Vite Hemarexin Amp MultiVitamin with Fluoride Chewable Natalvirt 90dha Natavite Tricare Prenatal 2-part Daily Prenatal Vitamin System Grand Master Formula Tab Multiple Vitamins Plus Iron Tab Omniquin Multiple Vitamins W Iron Tab Pnv-OB-dha Xvite DaVITE Dialyvite 3000 healthy mamaBE WELL ROUNDED BE WELL ROUNDED Multivitamin Drops with Fluoride Onccor RenaPlex Vitamin B Complex Plus 300mg Vitamin C NovaMV Multivitamin Escavite B With C 500 Cap Liqui B Complex Plus Vitamin B Complex Plus C 300mg Timed Release Flintstones Multiple Vitamins Tab Vitamin & Mineral Formula 1 Dietary Supplement Vitaplex Vitranol Adult Infuvite Multiple Vitamins Vita-B Pregvit Folic 5 Multi Flow Tablets TRONVite PreNatal 19 Mega 13 Multivitamin Formula Concept DHA B C Antistress Cap Kanga-B Vitamin B Group + C Kimchi Vitamin chewable multivitamin Vita-Pac Hyporyl - Tab Men's Animal Shapes Somarexin and C 1000 Cedevita Plus Vitamin Supplement Children's Chewable Multiple Vit.plus Iron MultiVitamin with Fluoride Thiamine HCL 100 mg Vitamine B1 100 Mg - Tablet Cda-21 Vitamins With Non-medicinal Probiotic Complex Men's Biomultiple Vitamin and Mineral Supplement Bugs Bunny and Friends Multiple Vitamins Permathene-12 - Caplet Vitafer - Liq B Plus C 300mg Timed Release Multi Spectrum - Tablet Trinatal Rx 1 Multisol Multi Vitamin and Mineral vitamin M.V.I. Pediatric Time Release B 100 Compound - Tablet B Plus C 300 mg Beminal Fortis Elx Nephron FA Vitaphil DHA Mega Vitaminerals B Complex With C 550mg Vitasure Vitamine Du Groupe B Plus Fer - Liq Adeks Tablets Lipo-B-C Tab Lysamine Diet Supp Amp-tab Kids Stuff Tablets Infantol Drops New Chapter's D'adamo 4 Your Type Multiple for Type O DuetDHA Balanced Floriva Kanga-kid Vitamins & Iron Stress B With 1000 Mg Vitamin C Stressmates WesNatal DHA Complete Fortamines 10 Capsules Kanga-kid Multi-vitamin & Mineral For Kids Only Chewable Multivitamins Genicin Vita-S Essential Vitamins and Minerals Vitalife - Capsule Bugs Bunny Chew Multi Vit Plus Iron Omega-3 Rx Complete Vitachrom Gc Balanced B-50 B-complex Vitamins Tab Thiamine Hydrochloride Inj 100mg/ml USP B50 Complex PNV Ferrous Fumarate Docusate Folic Acid Stress B&c Tab Vita Vim With Beta Carotene-caplet Multinate DHA Extra Poly-Vite Pediatric Oral Solution B Complex W Vit C W Non-med Yeast&liver Tab TL-Fluorivite Mebolic Vyqua Harvest Of Values All B Complex Tab One Per Day Vitamin and Mineral Dietary Supplement Super-pote Vitamin Supplement Multivitamines Et Mineraux Reguliers / Regular Multivitamins and Minerals Children's Chewable Multiple Vitamins (chewable Tablets) Multiple Vitamins W Minerals Tab Multi Vitamin Drops with Fluoride with Iron Vege Swiss One Multivitamin W Chel Mins Tab Formula Lf Vita Vim Multivitamins and Minerals Tab Children's Chewable Multivitamins and Minerals Complexe B Compose 75 Central-vite 18 Essential Formula F L W Iberet 500 Zintrexyl-C Multicaps P.R.O. Complex Complete-RF Prenatal Multivitamin & Multimineral THIAMINE HCl Vitamines Et Mineraux Enfants 970 Thiamine Hydrochloride Vitamin B1 Tablets 100mg Vitafol Fe Plus Phosthenine Vitamines Et Fer (ampoules Buvable) Multinate DHA Children's Chewable Multi Vitamins With Iron Tablets Vitogen B Stress C Vit E Zinc & Cop Dexatran One-A-day Advance Fem - Tablets C-force Neomultivite Swiss One Multivitamin and Mineral Caplet Allbee With C 550 Cap Poly-Vite/Iron Oral Solution Multi-Vit-Flor Chewable Multiple Vit Plus Iron for Children Formula Gly Vitramyn Vena-Bal DHA Niva-Plus Multiple Vitamins and Minerals Formula Gm Poly-Vi-Sol Swiss One B Vitamin Compound With B12 Thunas C.R.T. X Multivitamin & Mineral Powder Mix Prena1 Plus PureVit DualFe Plus Viva CT Prenatal Supravite 10ml Ampoule Thrivite Rx CitraNatal DHA SetonET Vitamin B Complex + C 600mg Tab Vol-Tab Rx Phytovim Cap Multiple Vitamins With Iron Tablets Complete Mega B Hi Potency B Complex W Chelated Minerals Livita Adults Geritol Liquid Multiple Vit Plus Iron Tab Tricare Prenatal DHA One Rx Multivitamin Am Caps Multipack II B Complex 50+ Caplet OB Complete Petite B-100 Hi Potency B Vitamins Tab Zeldana Pregvit Folic 4 Chela Potassium Plus Fortistress Tab Stress Formula Multi-B Comp + 500mg Vit C Cap Iron Polysaccharides Folic Acid DHA Foliflex Hi Potency B52 B Complex Tab Re Ob 90 DHA B50 B Complex Tab B-complex With Vitamin C, Biotin, Folic Acid High Potency Multivitamins & Minerals Caplets Pro His Mint Earthpals Children's Chewables Multi-vitamin & Mineral Tablets Xyzbac G Foltabs Prenatal Plus DHA MultiVitamin with Fluoride Drops Vitazyme Ventrixyl Vol-Nate Pediatric Infuvite Multiple Vitamins TriAdvance Vitafol Caplet Vitamin B Complex 50 Acti-thiamine Caplet 100mg Methaver Multiple Vitamins and Minerals Capsules Multi-Vitamin Osteo-force One A Day Advance Fem PR Natal 400 Super Pantoplex Dialyvite 5000 Multivitamins and Minerals With Betacarotene Tablets OBTREX DHA Combo Pack CitraNatal Rx Flintstones W Extra C Tab Natal-V RX Multi-vitamin/Multi-mineral Supravite Stress Avec Vit E Venexa FE Multi-force for Adults Tab NESTABS Prenatal Multi-vitamin/Mineral Supplement Hi Potency Balanced B-100 Complex - Tab Dayavite Multi II IV Vi Tab 50 Plus Multiple Vitamins & Minerals Original Bioscal Forte Multi-vitamin Supplement Capsules
Indication	For the treatment of thiamine and niacin deficiency states, Korsakov's alcoholic psychosis, Wernicke-Korsakov syndrome, delirium, and peripheral neuritis.
Categories	Alimentary Tract and Metabolism Diet, Food, and Nutrition Food Growth Substances Micronutrients OCT1 substrates OCT2 Inhibitors Physiological Phenomena Pyrimidines Sulfur Compounds Thiazoles Vitamin B Complex Vitamins
ATC-Code	A11DA01
CAS number	70-16-6

Drug Targets

Name	Target Sequence	Pharmacological Action	Actions
Thiamine pyrophosphokinase 1	MEHAFTPLEPLLSTGNLKYCLVILNQPLDNYFRHLWNKALLRACADGGAN...	unknown	substrate
Pyruvate dehydrogenase E1 component	MSERFPNDVDPIETRDWLQAIESVIREEGVERAQYLIDQLLAEARKGGVN...	unknown	cofactor
Cytochrome P450 4B1	MVPSFLSLSFSSLGLWASGLILVLGFLKLIHLLLRRQTLAKAMDKFPGPP...	unknown	inducer
Thiamine pyrophosphokinase 1	MEHAFTPLEPLLSTGNLKYCLVILNQPLDNYFRHLWNKALLRACADGGAN...	unknown	substrate
Nucleoside diphosphate phosphatase ENTPD5	MATSWGTVFFMLVVSCVCSAVSHRNQQTWFEGIFLSSMCPINVSASTLYG...	unknown	substrate
Thiamine-triphosphatase	MAQGLIEVERKFLPGPGTEERLQELGGTLEYRVTFRDTYYDTPELSLMQA...	unknown	substrate
Albumin	MKWVTFISLLFLFSSAYSRGVFRRDAHKSEVAHRFKDLGEENFKALVLIA...	unknown	binder
Solute carrier family 22 member 2	MPTTVDDVLEHGGEFHFFQKQMFFLLALLSATFAPIYVGIVFLGFTPDHR...	unknown	inhibitor
Solute carrier family 22 member 1	MPTVDDILEQVGESGWFQKQAFLILCLLSAAFAPICVGIVFLGFTPDHHC...	unknown	substrate
Organic cation/carnitine transporter 2	MRDYDEVTAFLGEWGPFQRLIFFLLSASIIPNGFTGLSSVFLIATPEHRC...	unknown	inhibitor
Thiamine transporter 1	MDVPGPVSRRAAAAAATVLLRTARVRRECWFLPTALLCAYGFFASLRPSE...	unknown	substrate
Thiamine transporter 2	MDCYRTSLSSSWIYPTVILCLFGFFSMMRPSEPFLIPYLSGPDKNLTSAE...	unknown	substrate
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Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682