Chemical Component Summary

Name5,5-diethyl-1-methyl-1,3-diazinane-2,4,6-trione
Identifiers5,5-diethyl-1-methyl-1,3-diazinane-2,4,6-trione
FormulaC9 H14 N2 O3
Molecular Weight198.219
TypeNON-POLYMER
Isomeric SMILESCCC1(C(=O)NC(=O)N(C1=O)C)CC
InChIInChI=1S/C9H14N2O3/c1-4-9(5-2)6(12)10-8(14)11(3)7(9)13/h4-5H2,1-3H3,(H,10,12,14)
InChIKeyFWJKNZONDWOGMI-UHFFFAOYSA-N

Chemical Details

Formal Charge0
Atom Count28
Chiral Atom Count0
Bond Count28
Aromatic Bond Count0

Drug Info: DrugBank

DrugBank IDDB00463 
NameMetharbital
Groups withdrawn
DescriptionMetharbital is a barbiturate anticonvulsant, similar to phenobarbital, marketed as Gemonil by Abbott Laboratories. It was patented in 1905 by Emil Fischer of Merck.
Synonyms
  • Metharbital
  • Metharbitalum
  • Metarbital
IndicationMetharbital is used for the treatment of epilepsy.
Categories
  • Anticholinergic Agents
  • Anticonvulsants
  • Barbiturates and Derivatives
  • Central Nervous System Depressants
  • Nervous System
ATC-CodeN03AA30
CAS number50-11-3

Drug Targets

NameTarget SequencePharmacological ActionActions
Gamma-aminobutyric acid receptor subunit alpha-2MKTKLNIYNMQFLLFVFLVWDPARLVLANIQEDEAKNNITIFTRILDRLL...unknownpotentiator
Gamma-aminobutyric acid receptor subunit alpha-3MIITQTSHCYMTSLGILFLINILPGTTGQGESRRQEPGDFVKQDIGGLSP...unknownpotentiator
Gamma-aminobutyric acid receptor subunit alpha-4MVSAKKVPAIALSAGVSFALLRFLCLAVCLNESPGQNQKEEKLCTENFTR...unknownpotentiator
Gamma-aminobutyric acid receptor subunit alpha-5MDNGMFSGFIMIKNLLLFCISMNLSSHFGFSQMPTSSVKDETNDNITIFT...unknownpotentiator
Gamma-aminobutyric acid receptor subunit alpha-6MASSLPWLCIILWLENALGKLEVEGNFYSENVSRILDNLLEGYDNRLRPG...unknownpotentiator
View More
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682

Related Resource References

Resource NameReference
Pharos CHEMBL450
PubChem 4099
ChEMBL CHEMBL450
ChEBI CHEBI:31827
CCDC/CSD MDEBAR