DrugBank ID DB00878 Name Chlorhexidine Groups approved vet_approved withdrawn Description Chlorhexidine is a broad-spectrum antimicrobial biguanide used as a topical antiseptic and in dental practice for the treatment of inflammatory dental conditions caused by microorganisms.[L11512] It is one of the most common skin and mucous membrane antiseptic agents in use today.[A190417] The molecule itself is a cationic bis-guanide consisting of two 4-chlorophenyl rings and two biguanide groups joined by a central hexamethylene chain.[A190453] Topical chlorhexidine for disinfection, as well as oral rinses for dental use, carries activity against a broad range of pathogens including bacteria, yeasts, and viruses.[L11518,L11512,A190453] Chlorhexidine was developed in the UK by Imperial Chemical Industries in the early 1950s[A190474] and was introduced to the US in the 1970s.[L11572] The FDA withdrew its approval for the use of chlorhexidine gluconate topical tincture 0.5%, due to a significant number of reports concerning chemical and thermal burns associated with the use of this product.[L43942,L44027] Other formulations of chlorhexidine continue to be available. Synonyms more Brand Names Chlorhexidine Liq 0.05% Jisberry Hand Sanitizer Peridex Oral Rinse Anti Mucedine Feminine Wash CLIP Liquid Sanitizer
Loris I.V. Pro - Prefilled Applicator With Solution Hibiclens Hexirex Antiseptic Skin Cleanser Endure 420 Cida-Stat Tai Yu Ling Antibacterial Sprays 10mL Betasept Protective Hand Gum Paroex Noble 75% Alcohol Wipes CliniClean Antiseptic Body Cleanser Spray On Plastic Bandage Aerosol Chinese Herb Essence Bacteriostatic Feminine Wash Hand Sanitizer Biokaab Antimicrobial Skin Cleanser Skin Antisepsis, Oral Cleansing and Nasal Antisepsis System Soluprep Ld Sponge Soluprep Antiseptic Skin Cleanser Preoperative Kit Skin antisepsis, oral cleansing, nasal antisepsis Quick-Drying Hand Sanitizer Prevantics swabstick Sanital Antibacterial Hand Soap Foam Care Chg Surgical Hand Scrub DEQGEL Advanced Hand Sanitizer (Fruli) Quick-Dry Disposable Hand Sanitizer Maxiclens Chlorhexidine gluconate Liquid Solution, 4% Bacti-stat Chg Eyewash Station Additive Concentrate Chlorhexidine Gluconate Applicator Hygenipak 2% Chg Foaming Skin Cleanser Skinvisible Chlorhexidine Formula Hand Sanitizer Lotion Pre-moistened Towelette Scrub-stat IV 4% Hibitane Skin Cleanser 4% PS2 Aciurgy Pack Dr. Zheng s acteriostatic gel Chlorhexidine Gluconate Solution USP 20% LARA MED Antibacterial Wet Wipes Oral Cleansing and Suctioning System, q4 Antiseptic Foam Handwash Baxedin Liq 20% Stanhexidine 20% 3m Soluprep Sponge Hibitane Skin Cleanser 2% Chlorhexidine gluconate SAITENM Health Wet wipes Aplicare Antiseptic Chlorhexidine Gluconate Antiseptic Lotion Soap 2% Gelato Chlorohexidine Antimicrobial Foam Handwash Avidene Surgical Scrub Disinfectant Wet Tissues Germi Stat Gel 2% Purmist Disinfectant Fabric Wash Soluprep Wipe Sterixin 0.05% Chloraprep Swabsticks Cardinal Health Antiseptic Skin Cleanser Scrub Chlorhexidine Gluconate 0.12% Oral Rinse Hand Sanitizer Dermawerx Surgical PrePak Savlon Hospital Concentrate Hygenipak 2% Chg Skin Cleanser CleanCare Chlorhexidine Gluconate 0.12% Oral Rinse Wart Remover Ointment. Loris 2% Chg Solution E-Z Scrub 107 DermacinRx Clorhexacin Dr. Luke Molluscum Wart Remover Periogard Alcohol Free Burn O Sol Spray Cida-stat Liq Soft Care Antiseptic Hand Soap Chlorhexidine 0.5% Liq Rougier Clean Derm Wart removal Foam Safe Bactoshield Chg 4% Hibitane Skin Cleanser BD E-Z Scrub 107 Laura Line Antibacterial Cream Soap 2% Liszt Hand sanitizer without washing Hexifoam-skin Disinfectant Aer 1% Dexidin 2 Solution Scrub Care Exidine-2 CHG Soft Care 2% Chg Antimicrobial Skin Cleanser Medifresh Hand Skin Antiseptic Disinfectant Wet Wipes Freeman Packing Alcohol Wipe Rouhex G 20% Dexidin 20 ReadyPrep CHG Wart Removal Pen ICEKING Skin Expert Refreshing Body Roller Steri-clean Smart San CHG Antiseptic Skin Cleanser Smart Sense Antiseptic Skin Cleanser X-pur Chlorhexidine Prevantics Swab Prevantics Maxi Swabstick WhyteDerm SurgiPak PS1 Aciurgy Pack Soluprep QCare Rx Oral Cleansing and Suctioning System, Q4 Steri-stat Liq 4.0% Cida-stat Foam Hibiclens for Georgia Pacific Surgical and healthcare personnel hand antiseptic with moisturizers Loris 2% Chg Body Cleanser/nettoyant Pour Le Corps Soluprep Applicator Sunberry Rinse free Hand Sanitizer Akilgeld Hand Sanitizer Ic-gel Akilspray Hand Sanitizer Baxedin Peridex PerioChip Maxiclens Chlorhexidine Gluconate Liquid Solution, 4% Chlorhexidine Alcohol Free Selpak Antibacterial Wet Wipes Alcohol Antibacterial Wipes JIANLIANG Antibacterial Sprays 10mL Oral Cleansing and Suctioning System, q2 Foaming Hand Antiseptic With Chg 2% Rouhex G 4% Steri-stat Tincture (tinted) Antis Prep Gel Purell CS Foam Handwash 2% CHG 3M Avagard Hands-free skin sanitizer Loris I.V. Pro - Swabstick Perichlor Without Alcohol Chlorhexidine Solution Scrub Stat 4 Foam Liq PhysiciansCare Eyewash Station Additive Concentrate Chlorhexidine Gluconate Solution 0.05% Bactoshield Chg 2% Ultrastat Soluprep Qd Wipe Rouhex G Liq 2% BD E-Z Scrub Soluprep Qd Swab Prevora Stage 1 Soluprep Swab Periogard Liquivida Hydration Laura Line Chlorhexidine Antiseptic Soap Germi-stat 2% Foaming Liquid 3M SoluPrep Dermawerx Surgical Plus Pak Calgon Vestal 4% Chg Antimicrob.skin Cleans. Scrub Care Exidine -4 CHG Dyna-hex 2 DermacinRx Surgical ComboPak QCare Rx Petite Oral Cleansing and Suctioning System Hibistat Stat Touch 2 Antimicrobial Skin Cleanser Bioprep Bei Ling Tong Bao Er Zheng Yuan Antibacterial Creams Hand Wipes Stanhexidine 2% With Isopropyl Alcohol 4% Soluprep AQ Sponge ChloraPrep One-Step Disinfectant Spray(Speedy effect type) Cardinal Health Flamazine C Hygienium Dexidin 2 Detergent Chlora-cleanze Oro Clear Zedoary Oils Feminine Antibacterial Gels Soluprep Antiseptic Skin Cleanser Sponge Chlorhexidine Gluconate, 0.12% Oral Rinse Oro-clense NUPRO Chlorhexidine Gluconate Denti-Care Denti-Rinse Chlorhexidine Gluconate Oral Rinse Perichlor Hibiclens Antiseptic/antimicrobial Skin Cleanser Savlodil Alcohol Disinfectant Wipes Antiseptic Solution Bactoshield CHG Chlorhexidine Gluconate Solution Chlorhexidine Gluconante Scrub, Scrub-Stat Avagard Chg Quick-drying rinse-free hand skin disinfectant Antiseptic Skin Cleanser Exidine-2 CHG Spray On Plastic Bandage Non-aerosol Denticare Chlorhexidine Gluconate Oral Rinse 0.12% Antiseptic First Aid Spray Dyna-Hex 4 Antiseptic Cleansing Wipes Soluprep Qd Solution Hibitane Skin Cleanser Liq 4% Provon Antimicrobial Foam Handwash Chlorhexidine 2% Antiseptic Hand Wash Dr. Luke Wart Remover Stanhexidine 4% With Isopropyl Alcohol 4% 3M SoluPrep S Microban Medical Calgon Vestal 2% Chg Antimicrob.skin Cleans. Paroex Hygienipak 4% Chg Skin Cleanser Loris 2% Chg Wipe/serviette DermacinRx Surgical PharmaPak Chlorhexidine Gluconate Oral Rinse E-Z Scrub Antimicrobial Foam Solution Containing 4% Chg Germi-stat Prep Gel Scrub Care Surgical Scrub Brush/nail Cleaner With Exidine 4 Kimvent Oral Care Q2 Kit with CHG Salvesept Crm Peridex Oral Rinse 0.12% Soluprep AQ Swab Chlorhexidine Gluconate Ostar Antimicrobial Hand Soap 2% - Liquid Euro-chlorhexidine Acclean Chlorhexidine Gluconate 0.12% Oral Rinse Serdaen Stanhexidine Aqueous 2% With 4% Isopropyl Alcohol Rugby Antiseptic Skin Cleanser Sky Oral Rinse Baxedin Pre-OP Dermsafe Pc E-Z Scrub 747 4% Provon Antiseptic Lotion Soap With 2% Chg Solunet C Brosse 4% KleerSight Surgical Continuum System Hibistat Germicidal Hand Rinse Scrub-Stat Hygienipak 4% Chg Foaming Skin Cleanser NuSurgePak Surgical Prep/CarePak Dyna-hex 4 Baxedin 2% - 70% Steri-stat Liq 20% Purell Antimicrobial Foam Handwash 2% Chg SANIDEP Advanced Sanitizer with Organic Extracts Germi-stat 0.5% Antiseptic Prep Gel Dexidin 0.5 Solution Chlorhexidine and Isopropyl Alcohol Swabsticks Dermsafe Chlorhexidine Gluconate Hand Sanitizer Lotion Anti-bac Hand Hexicinide Soluprep AQ Wipe Foaming Chlorhexidine Gluconate Steri-stat Liq 2.0% Instillagel Chlorhexidine Gluconate Solution 0.75% Antiseptic Chlorhexidine 4% Antiseptic Hand Wash Chlorhexidine Gluconate, 0.12% Oral Rinse Solution Chlorhexidine-cetrimide Soltn Conc B-good Hand and Skin Disinfecting Agent Aplicare Chlorhexidine Gluconate 2% Solution Chlorhexidine Gluconate 0.12% Oral Rinse, USP Rougier Vap-chlorhexidine Gluconate 2% W/V QCare Rx Oral Cleansing and Suctioning System, Q2 Chlorhexseptic-liq 0.5mg/ml Pro-dentx Chlorhexidene Oral Rinse Purell Antimicrobial Foam Bactoshield CHG Chlorhexidine Gluconate Antibacterial Protective Hand Chloraprep Chlorhexidine and Isopropyl Alcohol Prep Pads Pre-Scrub II Surgical Hand Scrub Dyna-Hex 75 Antiseptic Cleanser Solution Foaming Hand Wash Chlorhexidine Dyna-Hex 2 Dexidin Liq 4% Stanhexidine Red Tincture 0.5% First Aid Antiseptic Skin Cleanser Foster and Thrive Henry Schein Antimicrobial Skin Cleanser Dr. Dean Hand wipes DASH Chlorhexidine Gluconate 0.12% Oral Rinse Bactoshield Soluprep AQ Scrub Care Hibidil Loris I.V. Pro - Sponge Endure 400 Scrub-Stat 4 Soluprep AQ Applicator Q2 Oral Care Kit with CHG Spectro Gram 2 Skin Cleanser Chloraprep Liq 0.5% Yu Ding Antibacterial Sprays 10mL Spectro Tar Antiseptic Shampoo Germi Stat Gel 4% Seaqua X Loris - I.V. Scrub, Scrub-Stat, Foam Safe, Micro-Guard Motherwort Herb Feminine Antibacterial Gels KIMVENT ORAL CARE Q4 Kit WITH CHG (Qiqing) Chlorhexidine Gluconate Alcohol Disinfectant Prevantics Swabstick Major Oral Rinse QCare Rx Oral Cleansing and Suctioning System Oris Chx Ezy-TM Periogard (Chlorhexidine Gluconate) Perioselect Antimicrobial Sol 0.12% Septi-san Pre and Post Sx Pouch Plant Herb Based Bacteriostatic Feminine Wash Bactigras Bioprep Liq Bactoshield CHG Sterigel Plus HandSoap Oronine H Ointment 1% Hand Sanitizer Gel Biokaab more Indication Chlorhexidine is available over-the-counter in various formulations (e.g. solution, sponge, cloth, swab) as a topical antiseptic to sanitize prior to surgeries and/or medical procedures.[L11518,L11521,L11527,L11533] Dental formulations, available by prescription only, include an oral rinse indicated for the treatment of gingivitis[L11512] and a slow-release "chip" which is inserted into periodontal pockets and is indicated for the reduction of pocket depth in adult patients with periodontitis as an adjunct therapy to dental scaling and root planing procedures.[L11536] Categories Alimentary Tract and Metabolism Amidines Anti-Infective Agents Anti-Infective Agents, Local Antiinfectives and Antiseptics for Local Oral Treatment
Antiseptics and Disinfectants Biguanides Biguanides and Amidines Compounds used in a research, industrial, or household setting Decreased Cell Wall Integrity Dental Agents Dermatologicals Disinfectants Guanidines Household Products Irrigating Solutions Medicated Dressings Medicated Dressings With Antiinfectives Miscellaneous Anti-infectives Miscellaneous Local Anti-infectives Mouthwashes Mouthwashes and Gargles Ophthalmological and Otological Preparations Ophthalmologicals Otologicals Sensory Organs Stomatological Preparations Throat Preparations more ATC-Code more CAS number 55-56-1 
