Download MendeleySaicar Synthase: Substrate Recognition, Conformational Flexibility and Catalysis.
Urusova, D.V., Antonyuk, S.V., Grebenko, A.I., Levdikov, V.M., Barynin, V.V., Popov, A.N., Lamzin, V.S., Melik-Adamyan, W.R.To be published.
2CNU
Atomic resolution structure of SAICAR-synthase from Saccharomyces cerevisiae complexed with aspartic acid
- PDB DOI: https://doi.org/10.2210/pdb2CNU/pdb
- Classification: LIGASE
- Organism(s): Saccharomyces cerevisiae
- Mutation(s): No
- Deposited: 2006-05-24 Released: 2006-06-07
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 1.05 Å
- R-Value Free: 0.159
- R-Value Work: 0.132
- R-Value Observed: 0.134
Starting Model: experimental
View more details
wwPDB Validation 3D Report Full Report
This is version 1.4 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| PHOSPHORIBOSYLAMINOIMIDAZOLE-SUCCINOCARBOXAMIDE SYNTHASE | 306 | Saccharomyces cerevisiae | Mutation(s): 0 EC: 6.3.2.6 |  | |
UniProt | |||||
Find proteins for P27616 (Saccharomyces cerevisiae (strain ATCC 204508 / S288c)) Explore P27616 Go to UniProtKB: P27616 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P27616 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 2 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| ASP Query on ASP | B [auth A], C [auth A], D [auth A] | ASPARTIC ACID C4 H7 N O4 CKLJMWTZIZZHCS-REOHCLBHSA-N |  | ||
| SO4 Query on SO4 | E [auth A] F [auth A] G [auth A] H [auth A] I [auth A] | SULFATE ION O4 S QAOWNCQODCNURD-UHFFFAOYSA-L |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 1.05 Å
- R-Value Free: 0.159
- R-Value Work: 0.132
- R-Value Observed: 0.134
- Space Group: P 21 21 21
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 61.023 | α = 90 |
| b = 62.497 | β = 90 |
| c = 78.273 | γ = 90 |
| Software Name | Purpose |
|---|---|
| REFMAC | refinement |
| DENZO | data reduction |
| SCALEPACK | data scaling |
| MOLREP | phasing |
Entry History
Deposition Data
- Released Date: 2006-06-07 Deposition Author(s): Urusova, D.V., Antonyuk, S.V., Grebenko, A.I., Levdikov, V.M., Barynin, V.V., Popov, A.N., Lamzin, V.S., Melik-Adamyan, W.R.
Revision History (Full details and data files)
- Version 1.0: 2006-06-07
Type: Initial release - Version 1.1: 2013-09-04
Changes: Atomic model, Derived calculations, Non-polymer description, Other, Structure summary, Version format compliance - Version 1.2: 2019-07-24
Changes: Data collection, Derived calculations - Version 1.3: 2023-12-13
Changes: Data collection, Database references, Derived calculations, Other, Refinement description - Version 1.4: 2024-11-06
Changes: Structure summary
