2GF2

Crystal structure of human hydroxyisobutyrate dehydrogenase

Experimental Data Snapshot

  • Method: X-RAY DIFFRACTION
  • Resolution: 2.38 Å
  • R-Value Free: 0.247 
  • R-Value Work: 0.205 
  • R-Value Observed: 0.207 

wwPDB Validation   3D Report Full Report


This is version 1.3 of the entry. See complete history. 


Literature

Crystal structure of human hydroxyisobutyrate dehydrogenase

Papagrigoriou, E., Salah, E., Turnbull, A.P., Smee, C., Burgess, N., Gileadi, O., von Delft, F., Gorrec, F., Arrowsmith, C.H., Weigelt, J., Sundstrom, M., Edwards, A.M., Oppermann, U.

To be published.

Macromolecules
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(by identity cutoff)  |  3D Structure
Entity ID: 1
MoleculeChains Sequence LengthOrganismDetailsImage
3-hydroxyisobutyrate dehydrogenase
A, B, C, D
296Homo sapiensMutation(s): 0 
Gene Names: HIBADH
EC: 1.1.1.31
UniProt & NIH Common Fund Data Resources
Find proteins for P31937 (Homo sapiens)
Explore P31937 
Go to UniProtKB:  P31937
PHAROS:  P31937
GTEx:  ENSG00000106049 
Entity Groups  
Sequence Clusters30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt GroupP31937
Sequence Annotations
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  • Reference Sequence
Experimental Data & Validation

Experimental Data

  • Method: X-RAY DIFFRACTION
  • Resolution: 2.38 Å
  • R-Value Free: 0.247 
  • R-Value Work: 0.205 
  • R-Value Observed: 0.207 
  • Space Group: P 21 21 21
Unit Cell:
Length ( Å )Angle ( ˚ )
a = 50.053α = 90
b = 122.745β = 90
c = 200.397γ = 90
Software Package:
Software NamePurpose
REFMACrefinement
HKL-2000data reduction
HKL-2000data scaling
PHASERphasing

Structure Validation

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Entry History 

Deposition Data

Revision History  (Full details and data files)

  • Version 1.0: 2006-04-04
    Type: Initial release
  • Version 1.1: 2008-05-01
    Changes: Version format compliance
  • Version 1.2: 2011-07-13
    Changes: Version format compliance
  • Version 1.3: 2024-02-14
    Changes: Data collection, Database references, Refinement description