Download MendeleyTryptophan synthase complexed with IGP, internal aldimine, pH 9.0.
Kulik, V., Barends, T.R.M., Schlichting, I.To be published.
2RH9
Tryptophan synthase complexed with IGP, internal aldimine, pH 9.0
- PDB DOI: https://doi.org/10.2210/pdb2RH9/pdb
- Classification: LYASE
- Organism(s): Salmonella enterica subsp. enterica serovar Typhimurium
- Expression System: Escherichia coli
- Mutation(s): No
- Deposited: 2007-10-08 Released: 2007-11-06
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 1.70 Å
- R-Value Free: 0.200
- R-Value Work: 0.172
- R-Value Observed: 0.173
This is version 1.1 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Tryptophan synthase alpha chain | 268 | Salmonella enterica subsp. enterica serovar Typhimurium | Mutation(s): 0 Gene Names: trpA, STM1727 EC: 4.2.1.20 |  | |
UniProt | |||||
Find proteins for P00929 (Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)) Explore P00929 Go to UniProtKB: P00929 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P00929 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 2 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Tryptophan synthase beta chain | 397 | Salmonella enterica subsp. enterica serovar Typhimurium | Mutation(s): 0 Gene Names: trpB, STM1726 EC: 4.2.1.20 |  | |
UniProt | |||||
Find proteins for P0A2K1 (Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)) Explore P0A2K1 Go to UniProtKB: P0A2K1 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P0A2K1 | ||||
Sequence AnnotationsExpand | |||||
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Small Molecules
| Ligands 3 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| IGP Query on IGP | C [auth A] | INDOLE-3-GLYCEROL PHOSPHATE C11 H14 N O6 P NQEQTYPJSIEPHW-MNOVXSKESA-N |  | ||
| PLP Query on PLP | E [auth B] | PYRIDOXAL-5'-PHOSPHATE C8 H10 N O6 P NGVDGCNFYWLIFO-UHFFFAOYSA-N |  | ||
| NA Query on NA | D [auth B] | SODIUM ION Na FKNQFGJONOIPTF-UHFFFAOYSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 1.70 Å
- R-Value Free: 0.200
- R-Value Work: 0.172
- R-Value Observed: 0.173
- Space Group: C 1 2 1
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 183.071 | α = 90 |
| b = 59.281 | β = 94.67 |
| c = 67.345 | γ = 90 |
| Software Name | Purpose |
|---|---|
| REFMAC | refinement |
| ADSC | data collection |
| XDS | data reduction |
| XSCALE | data scaling |
| CNS | phasing |
Entry History
Deposition Data
- Released Date: 2007-11-06 Deposition Author(s): Kulik, V., Barends, T.R.M., Schlichting, I.
Revision History (Full details and data files)
- Version 1.0: 2007-11-06
Type: Initial release - Version 1.1: 2011-07-13
Changes: Non-polymer description, Version format compliance
