Download MendeleyHuman PPAR gamma ligand binding dmain complexed with GW9662 in a covalent bonded form
Shimizu, T.To be published.
3B0R
Human PPAR gamma ligand binding dmain complexed with GW9662 in a covalent bonded form
- PDB DOI: https://doi.org/10.2210/pdb3B0R/pdb
- Classification: TRANSCRIPTION
- Organism(s): Homo sapiens
- Expression System: Escherichia coli
- Mutation(s): No
- Deposited: 2011-06-13 Released: 2011-08-10
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.15 Å
- R-Value Free: 0.249
- R-Value Work: 0.207
- R-Value Observed: 0.209
Starting Model: experimental
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This is version 1.2 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Peroxisome proliferator-activated receptor gamma | 274 | Homo sapiens | Mutation(s): 0 Gene Names: PPARG, NR1C3 |  | |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for P37231 (Homo sapiens) Explore P37231 Go to UniProtKB: P37231 | |||||
PHAROS: P37231 GTEx: ENSG00000132170 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P37231 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 1 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| GW9 Query on GW9 | C [auth A], D [auth B] | 2-chloro-5-nitro-N-phenylbenzamide C13 H9 Cl N2 O3 DNTSIBUQMRRYIU-UHFFFAOYSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.15 Å
- R-Value Free: 0.249
- R-Value Work: 0.207
- R-Value Observed: 0.209
- Space Group: C 1 2 1
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 92.7 | α = 90 |
| b = 59.801 | β = 103.6 |
| c = 117.255 | γ = 90 |
| Software Name | Purpose |
|---|---|
| HKL-2000 | data collection |
| MOLREP | phasing |
| REFMAC | refinement |
| HKL-2000 | data reduction |
| HKL-2000 | data scaling |
Entry History
Deposition Data
- Released Date: 2011-08-10 Deposition Author(s): Tomioka, D., Hashimoto, H., Sato, M., Shimizu, T.
Revision History (Full details and data files)
- Version 1.0: 2011-08-10
Type: Initial release - Version 1.1: 2023-11-01
Changes: Data collection, Database references, Derived calculations, Refinement description - Version 1.2: 2024-10-23
Changes: Structure summary
