Download MendeleyCrystal structure and biochemical characterization of M.tuberculosis ribokinase (Rv2436)
Masters, E.I., Sun, Y., Wang, Y., Parker, W.B., Li, R.To be published.
3GO7
Crystal Structure of M. tuberculosis ribokinase (Rv2436) in complex with ribose
- PDB DOI: https://doi.org/10.2210/pdb3GO7/pdb
- Classification: TRANSFERASE
- Organism(s): Mycobacterium tuberculosis
- Expression System: Escherichia coli
- Mutation(s): No
- Deposited: 2009-03-18 Released: 2010-03-31
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.50 Å
- R-Value Free: 0.237
- R-Value Work: 0.176
- R-Value Observed: 0.179
This is version 2.1 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| RIBOKINASE RBSK | 310 | Mycobacterium tuberculosis | Mutation(s): 0 Gene Names: rbsK, Rv2436 EC: 2.7.1.15 |  | |
UniProt | |||||
Find proteins for P71913 (Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)) Explore P71913 Go to UniProtKB: P71913 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P71913 | ||||
Sequence AnnotationsExpand | |||||
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Small Molecules
| Ligands 2 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| RIB Query on RIB | C [auth A] | alpha-D-ribofuranose C5 H10 O5 HMFHBZSHGGEWLO-AIHAYLRMSA-N |  | ||
| MG Query on MG | D [auth A], E [auth B] | MAGNESIUM ION Mg JLVVSXFLKOJNIY-UHFFFAOYSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.50 Å
- R-Value Free: 0.237
- R-Value Work: 0.176
- R-Value Observed: 0.179
- Space Group: C 1 2 1
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 79.025 | α = 90 |
| b = 119.207 | β = 115 |
| c = 89.768 | γ = 90 |
| Software Name | Purpose |
|---|---|
| DENZO | data reduction |
| SCALEPACK | data scaling |
| REFMAC | refinement |
| PDB_EXTRACT | data extraction |
| HKL-2000 | data collection |
| HKL-2000 | data reduction |
| HKL-2000 | data scaling |
Entry History
Deposition Data
- Released Date: 2010-03-31 Deposition Author(s): Masters, E.I., Sun, Y., Wang, Y., Parker, W.B., Li, R.
Revision History (Full details and data files)
- Version 1.0: 2010-03-31
Type: Initial release - Version 1.1: 2011-07-13
Changes: Version format compliance - Version 1.2: 2017-11-01
Changes: Refinement description - Version 1.3: 2018-01-24
Changes: Database references - Version 2.0: 2020-07-29
Type: Remediation
Reason: Carbohydrate remediation
Changes: Atomic model, Data collection, Database references, Derived calculations, Structure summary - Version 2.1: 2024-02-21
Changes: Data collection, Database references, Structure summary
