Download MendeleyDirect Reductive Amination of Ketones: Structure and Activity of S-Selective Imine Reductases from Streptomyces.
Huber, T., Schneider, L., Prag, A., Gerhardt, S., Einsle, O., Muller, M.(2014) ChemCatChem
4OQY
Streptomyces sp. GF3546 imine reductase
- PDB DOI: https://doi.org/10.2210/pdb4OQY/pdb
- Classification: OXIDOREDUCTASE
- Organism(s): Streptomyces sp. GF3546
- Expression System: Escherichia coli
- Mutation(s): No
- Deposited: 2014-02-10 Released: 2014-10-22
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 1.90 Å
- R-Value Free: 0.241
- R-Value Work: 0.216
- R-Value Observed: 0.218
This is version 1.5 of the entry. See complete history.
Literature
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| (S)-imine reductase | 290 | Streptomyces sp. GF3546 | Mutation(s): 0 |  | |
UniProt | |||||
Find proteins for M4ZS15 (Streptomyces sp. GF3546) Explore M4ZS15 Go to UniProtKB: M4ZS15 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | M4ZS15 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 1 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| NDP Query on NDP | C [auth A] | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE C21 H30 N7 O17 P3 ACFIXJIJDZMPPO-NNYOXOHSSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 1.90 Å
- R-Value Free: 0.241
- R-Value Work: 0.216
- R-Value Observed: 0.218
- Space Group: P 21 21 21
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 45.32 | α = 90 |
| b = 68.24 | β = 90 |
| c = 181.38 | γ = 90 |
| Software Name | Purpose |
|---|---|
| MOLREP | phasing |
| REFMAC | refinement |
| MOSFLM | data reduction |
| SCALA | data scaling |
Entry History
Deposition Data
- Released Date: 2014-10-22 Deposition Author(s): Schneider, L.K., Huber, T., Gerhardt, S., Muller, M., Einsle, O.
Revision History (Full details and data files)
- Version 1.0: 2014-10-22
Type: Initial release - Version 1.1: 2014-11-12
Changes: Other, Structure summary - Version 1.2: 2014-11-19
Changes: Other - Version 1.3: 2017-08-09
Changes: Structure summary - Version 1.4: 2017-11-22
Changes: Refinement description - Version 1.5: 2024-02-28
Changes: Data collection, Database references, Derived calculations, Refinement description
