Structure of Human Leukotriene A4 Hydrolase in complex with inhibitor H1
Ouyang, P., Lu, W., Cui, K., Huang, J.To be published.
Experimental Data Snapshot
Entity ID: 1 | |||||
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Molecule | Chains | Sequence Length | Organism | Details | Image |
Leukotriene A-4 hydrolase | 631 | Homo sapiens | Mutation(s): 0  Gene Names: LTA4H, LTA4 EC: 3.3.2.6 (PDB Primary Data), 3.4.11.4 (UniProt) | ||
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for P09960 (Homo sapiens) Explore P09960  Go to UniProtKB:  P09960 | |||||
PHAROS:  P09960 GTEx:  ENSG00000111144  | |||||
Entity Groups   | |||||
Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
UniProt Group | P09960 | ||||
Sequence AnnotationsExpand | |||||
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Ligands 5 Unique | |||||
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ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
B3N Query on B3N | B [auth A] | 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide C16 H25 N3 O3 MXWDSZWTBOCWBK-UHFFFAOYSA-N | |||
YB Query on YB | D [auth A] | YTTERBIUM (III) ION Yb AWSFICBXMUKWSK-UHFFFAOYSA-N | |||
IMD Query on IMD | F [auth A] | IMIDAZOLE C3 H5 N2 RAXXELZNTBOGNW-UHFFFAOYSA-O | |||
ZN Query on ZN | C [auth A] | ZINC ION Zn PTFCDOFLOPIGGS-UHFFFAOYSA-N | |||
ACY Query on ACY | E [auth A] | ACETIC ACID C2 H4 O2 QTBSBXVTEAMEQO-UHFFFAOYSA-N |
Length ( Å ) | Angle ( ˚ ) |
---|---|
a = 76.961 | α = 90 |
b = 86.803 | β = 90 |
c = 98.207 | γ = 90 |
Software Name | Purpose |
---|---|
HKL-2000 | data collection |
PHASES | phasing |
REFMAC | refinement |
HKL-2000 | data reduction |
HKL-2000 | data scaling |