Structural mechanism of hormone release in thyroxine Binding globulin
Zheng, Y.To be published.
Experimental Data Snapshot
Entity ID: 1 | |||||
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Molecule | Chains | Sequence Length | Organism | Details | Image |
Thyroxine-binding globulin | 375 | Homo sapiens | Mutation(s): 0  Gene Names: SERPINA7, TBG | ||
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for P05543 (Homo sapiens) Explore P05543  Go to UniProtKB:  P05543 | |||||
PHAROS:  P05543 GTEx:  ENSG00000123561  | |||||
Entity Groups   | |||||
Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
UniProt Group | P05543 | ||||
Sequence AnnotationsExpand | |||||
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Entity ID: 2 | |||||
---|---|---|---|---|---|
Molecule | Chains | Sequence Length | Organism | Details | Image |
Thyroxine-binding globulin | 34 | Homo sapiens | Mutation(s): 0  Gene Names: SERPINA7, TBG | ||
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for P05543 (Homo sapiens) Explore P05543  Go to UniProtKB:  P05543 | |||||
PHAROS:  P05543 GTEx:  ENSG00000123561  | |||||
Entity Groups   | |||||
Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
UniProt Group | P05543 | ||||
Sequence AnnotationsExpand | |||||
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Ligands 4 Unique | |||||
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ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
IMN Query on IMN | G [auth B] | INDOMETHACIN C19 H16 Cl N O4 CGIGDMFJXJATDK-UHFFFAOYSA-N | |||
CA Query on CA | C [auth A], H [auth B] | CALCIUM ION Ca BHPQYMZQTOCNFJ-UHFFFAOYSA-N | |||
CL Query on CL | F [auth A], I [auth B] | CHLORIDE ION Cl VEXZGXHMUGYJMC-UHFFFAOYSA-M | |||
NA Query on NA | D [auth A], E [auth A] | SODIUM ION Na FKNQFGJONOIPTF-UHFFFAOYSA-N |
Length ( Å ) | Angle ( ˚ ) |
---|---|
a = 41.98 | α = 90 |
b = 56.07 | β = 90 |
c = 173.36 | γ = 90 |
Software Name | Purpose |
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REFMAC | refinement |
MOSFLM | data reduction |
SCALEPACK | data scaling |
PHASER | phasing |
Funding Organization | Location | Grant Number |
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China | -- |