Download MendeleyCrystal structure of the murine cd44 hyaluronan binding domain complex with a small molecule
Liu, L.K., Finzel, B.C.To be published.
5BZJ
Crystal structure of the murine cd44 hyaluronan binding domain complex with a small molecule
- PDB DOI: https://doi.org/10.2210/pdb5BZJ/pdb
- Classification: PROTEIN BINDING
- Organism(s): Mus musculus
- Expression System: Escherichia coli BL21(DE3)
- Mutation(s): Yes
- Deposited: 2015-06-11 Released: 2016-06-29
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 1.40 Å
- R-Value Free: 0.209
- R-Value Work: 0.184
- R-Value Observed: 0.185
This is version 1.1 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| CD44 antigen | 151 | Mus musculus | Mutation(s): 2 Gene Names: Cd44, Ly-24 |  | |
UniProt | |||||
Find proteins for P15379 (Mus musculus) Explore P15379 Go to UniProtKB: P15379 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P15379 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 3 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| 4WN Query on 4WN | E [auth A] | 2-[2-(1-methyl-1H-imidazol-2-yl)ethyl]-1,2,3,4-tetrahydroisoquinolin-8-amine C15 H20 N4 JGJLPCQCNSYHGF-UHFFFAOYSA-N |  | ||
| SO4 Query on SO4 | C [auth A], D [auth A] | SULFATE ION O4 S QAOWNCQODCNURD-UHFFFAOYSA-L |  | ||
| DMS Query on DMS | B [auth A] | DIMETHYL SULFOXIDE C2 H6 O S IAZDPXIOMUYVGZ-UHFFFAOYSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 1.40 Å
- R-Value Free: 0.209
- R-Value Work: 0.184
- R-Value Observed: 0.185
- Space Group: P 1 21 1
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 30.871 | α = 90 |
| b = 81.503 | β = 118.11 |
| c = 32.181 | γ = 90 |
| Software Name | Purpose |
|---|---|
| SCALA | data scaling |
| PHASER | phasing |
| REFMAC | refinement |
| PDB_EXTRACT | data extraction |
Entry History
Deposition Data
- Released Date: 2016-06-29 Deposition Author(s): Liu, L.K., Finzel, B.C.
Revision History (Full details and data files)
- Version 1.0: 2016-06-29
Type: Initial release - Version 1.1: 2024-11-13
Changes: Data collection, Database references, Derived calculations, Structure summary
