Download MendeleyNeisseria meningitidis 3 dexy-D-arabino-heptulosonate 7-phosphate synthase Glu176Ala variant at 2.04 Angstroms resolution
Heyes, L.C., Parker, E.J.To be published.
5CZT
Neisseria meningitidis 3 dexy-D-arabino-heptulosonate 7-phosphate synthase Glu176Ala variant
- PDB DOI: https://doi.org/10.2210/pdb5CZT/pdb
- Classification: TRANSFERASE
- Organism(s): Neisseria meningitidis MC58
- Expression System: Escherichia coli
- Mutation(s): Yes
- Deposited: 2015-08-01 Released: 2016-08-10
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.04 Å
- R-Value Free: 0.206
- R-Value Work: 0.171
- R-Value Observed: 0.173
This is version 1.2 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Phospho-2-dehydro-3-deoxyheptonate aldolase | 351 | Neisseria meningitidis MC58 | Mutation(s): 1 Gene Names: aroG, NMB0307 EC: 2.5.1.54 |  | |
UniProt | |||||
Find proteins for Q9K169 (Neisseria meningitidis serogroup B (strain ATCC BAA-335 / MC58)) Explore Q9K169 Go to UniProtKB: Q9K169 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | Q9K169 | ||||
Sequence AnnotationsExpand | |||||
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Small Molecules
| Ligands 3 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| PHE Query on PHE | F [auth A], H [auth B], K [auth C], O [auth D] | PHENYLALANINE C9 H11 N O2 COLNVLDHVKWLRT-QMMMGPOBSA-N |  | ||
| MN Query on MN | E [auth A], G [auth B], I [auth C], L [auth D] | MANGANESE (II) ION Mn WAEMQWOKJMHJLA-UHFFFAOYSA-N |  | ||
| CL Query on CL | J [auth C], M [auth D], N [auth D] | CHLORIDE ION Cl VEXZGXHMUGYJMC-UHFFFAOYSA-M |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.04 Å
- R-Value Free: 0.206
- R-Value Work: 0.171
- R-Value Observed: 0.173
- Space Group: P 1 21 1
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 75.647 | α = 90 |
| b = 140.828 | β = 98.56 |
| c = 77.266 | γ = 90 |
| Software Name | Purpose |
|---|---|
| REFMAC | refinement |
| XDS | data reduction |
| Aimless | data scaling |
| PHASER | phasing |
Entry History
Deposition Data
- Released Date: 2016-08-10 Deposition Author(s): Heyes, L.C., Parker, E.J.
Revision History (Full details and data files)
- Version 1.0: 2016-08-10
Type: Initial release - Version 1.1: 2017-11-01
Changes: Author supporting evidence, Data collection, Derived calculations, Structure summary - Version 1.2: 2024-03-06
Changes: Data collection, Database references, Derived calculations
