Crystal structure of FTO-CHTB
Chai, J., Zhou, B., Liu, W., Han, Z.To be published.
Experimental Data Snapshot
Entity ID: 1 | |||||
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Molecule | Chains | Sequence Length | Organism | Details | Image |
Alpha-ketoglutarate-dependent dioxygenase FTO | 476 | Homo sapiens | Mutation(s): 0  Gene Names: FTO, KIAA1752 EC: 1.14.11 (PDB Primary Data), 1.14.11.53 (UniProt) | ||
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for Q9C0B1 (Homo sapiens) Explore Q9C0B1  Go to UniProtKB:  Q9C0B1 | |||||
PHAROS:  Q9C0B1 GTEx:  ENSG00000140718  | |||||
Entity Groups   | |||||
Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
UniProt Group | Q9C0B1 | ||||
Sequence AnnotationsExpand | |||||
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Ligands 4 Unique | |||||
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ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
FIJ Query on FIJ | C [auth A] | 4-chloranyl-6-[(2~{S})-6-chloranyl-2,4,4-trimethyl-7-oxidanyl-3~{H}-chromen-2-yl]benzene-1,3-diol C18 H18 Cl2 O4 VSHLILKLIDPGCI-SFHVURJKSA-N | |||
AKG Query on AKG | D [auth A] | 2-OXOGLUTARIC ACID C5 H6 O5 KPGXRSRHYNQIFN-UHFFFAOYSA-N | |||
SO4 Query on SO4 | B [auth A] | SULFATE ION O4 S QAOWNCQODCNURD-UHFFFAOYSA-L | |||
FE2 Query on FE2 | E [auth A] | FE (II) ION Fe CWYNVVGOOAEACU-UHFFFAOYSA-N |
Length ( Å ) | Angle ( ˚ ) |
---|---|
a = 142.218 | α = 90 |
b = 142.218 | β = 90 |
c = 83.028 | γ = 120 |
Software Name | Purpose |
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PHENIX | refinement |
HKL-2000 | data scaling |
PDB_EXTRACT | data extraction |
PHENIX | phasing |