Download MendeleyCrystal Strcutures of Prmt6 in Complex with Sah in Alternative Conformations
Bonnefond, L., Cura, V., Troffer-Charlier, N., Cavarelli, J.To be published.
5FQN
Crystal structure of M. musculus protein arginine methyltransferase PRMT6 with SAH at 1.65 Angstroms
- PDB DOI: https://doi.org/10.2210/pdb5FQN/pdb
- Classification: TRANSFERASE
- Organism(s): Mus musculus
- Expression System: Escherichia coli BL21(DE3)
- Mutation(s): Yes
- Deposited: 2015-12-14 Released: 2017-01-18
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 1.66 Å
- R-Value Free: 0.211
- R-Value Work: 0.178
- R-Value Observed: 0.179
Starting Model: experimental
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This is version 1.2 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| PROTEIN ARGININE METHYLTRANSFERASE 6 | 402 | Mus musculus | Mutation(s): 1 EC: 2.1.1 (PDB Primary Data), 2.1.1.125 (PDB Primary Data), 2.1.1.319 (UniProt) |  | |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for Q6NZB1 (Mus musculus) Explore Q6NZB1 Go to UniProtKB: Q6NZB1 | |||||
IMPC: MGI:2139971 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | Q6NZB1 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 1 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| SAH Query on SAH | B [auth A] | S-ADENOSYL-L-HOMOCYSTEINE C14 H20 N6 O5 S ZJUKTBDSGOFHSH-WFMPWKQPSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 1.66 Å
- R-Value Free: 0.211
- R-Value Work: 0.178
- R-Value Observed: 0.179
- Space Group: I 41
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 79.426 | α = 90 |
| b = 79.426 | β = 90 |
| c = 118.567 | γ = 90 |
| Software Name | Purpose |
|---|---|
| PHENIX | refinement |
| XDS | data reduction |
| Aimless | data scaling |
| PHASER | phasing |
Entry History
Deposition Data
- Released Date: 2017-01-18 Deposition Author(s): Bonnefond, L., Cavarelli, J.
Revision History (Full details and data files)
- Version 1.0: 2017-01-18
Type: Initial release - Version 1.1: 2024-01-10
Changes: Data collection, Database references, Derived calculations, Other, Refinement description - Version 1.2: 2024-11-13
Changes: Data collection, Structure summary
