Download MendeleyPanDDA analysis group deposition of ground-state model
Grosjean, H., Aimon, A., Krojer, T., Talon, R., Douangamath, A., Koekemoer, L., Arrowsmith, C.H., Edwards, A., Bountra, C., von Delft, F., Biggin, P.C.To be published.
5RK6
PanDDA analysis group deposition -- Crystal Structure of PHIP in complex with Z198194394
- PDB DOI: https://doi.org/10.2210/pdb5RK6/pdb
- Deposition Group: G_1002162 (changed state) ExploreG_1002162
- Classification: PROTEIN BINDING
- Organism(s): Homo sapiens
- Expression System: Escherichia coli
- Mutation(s): No
- Deposited: 2020-06-02 Released: 2020-06-17
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 1.24 Å
- R-Value Free: 0.211
- R-Value Work: 0.183
- R-Value Observed: 0.185
This is version 1.1 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| PH-interacting protein | 149 | Homo sapiens | Mutation(s): 0 Gene Names: PHIP, DCAF14, WDR11 |  | |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for Q8WWQ0 (Homo sapiens) Explore Q8WWQ0 Go to UniProtKB: Q8WWQ0 | |||||
PHAROS: Q8WWQ0 GTEx: ENSG00000146247 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | Q8WWQ0 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 1 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| O1M (Subject of Investigation/LOI) Query on O1M | B [auth A] | 4-(4-fluorophenyl)piperazine-1-carboxamide C11 H14 F N3 O XARVCWHXIZRCGB-UHFFFAOYSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 1.24 Å
- R-Value Free: 0.211
- R-Value Work: 0.183
- R-Value Observed: 0.185
- Space Group: C 1 2 1
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 81.475 | α = 90 |
| b = 27.18 | β = 100.28 |
| c = 56.076 | γ = 90 |
| Software Name | Purpose |
|---|---|
| BUSTER | refinement |
| Aimless | data scaling |
| PDB_EXTRACT | data extraction |
| XDS | data reduction |
| REFMAC | phasing |
Entry History
Deposition Data
- Released Date: 2020-06-17 Deposition Author(s): Grosjean, H., Aimon, A., Krojer, T., Talon, R., Douangamath, A., Koekemoer, L., Arrowsmith, C.H., Edwards, A., Bountra, C., von Delft, F., Biggin, P.C.
Revision History (Full details and data files)
- Version 1.0: 2020-06-17
Type: Initial release - Version 1.1: 2024-03-06
Changes: Data collection, Database references
