Crystal Structure Of I83E Meditope-Enabled Trastuzumab With Azido-PEG3-Meditope
Williams, J.C., Bzymek, K.P., Pucket, J., Avery, K.A., Ma, Y., Xie, J., Zer, C., Horne, D.To be published.
Experimental Data Snapshot
Starting Model: experimental
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wwPDB Validation   3D Report Full Report
Entity ID: 1 | |||||
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Molecule | Chains | Sequence Length | Organism | Details | Image |
Light Chain | 214 | Homo sapiens | Mutation(s): 0  | ||
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Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
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Entity ID: 2 | |||||
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Molecule | Chains | Sequence Length | Organism | Details | Image |
Heavy Chain | 223 | Homo sapiens | Mutation(s): 0  | ||
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Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
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Entity ID: 3 | |||||
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Molecule | Chains | Sequence Length | Organism | Details | Image |
Protein L | C [auth E] | 63 | Finegoldia magna | Mutation(s): 5  | |
UniProt | |||||
Find proteins for Q51918 (Finegoldia magna) Explore Q51918  Go to UniProtKB:  Q51918 | |||||
Entity Groups   | |||||
Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
UniProt Group | Q51918 | ||||
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Entity ID: 4 | |||||
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Molecule | Chains | Sequence Length | Organism | Details | Image |
Immunoglobulin G binding protein A | D [auth C] | 54 | Staphylococcus aureus | Mutation(s): 0  Gene Names: spa | |
UniProt | |||||
Find proteins for P02976 (Staphylococcus aureus (strain NCTC 8325 / PS 47)) Explore P02976  Go to UniProtKB:  P02976 | |||||
Entity Groups   | |||||
Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
UniProt Group | P02976 | ||||
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Find similar proteins by: Sequence | 3D Structure
Entity ID: 5 | |||||
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Molecule | Chains | Sequence Length | Organism | Details | Image |
meditope peptide | E [auth D] | 14 | synthetic construct | Mutation(s): 0  | |
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Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
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Ligands 1 Unique | |||||
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ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
MRY Query on MRY | F [auth B] | MESO-ERYTHRITOL C4 H10 O4 UNXHWFMMPAWVPI-ZXZARUISSA-N |
Modified Residues 1 Unique | |||||
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ID | Chains | Type | Formula | 2D Diagram | Parent |
2GX Query on 2GX | E [auth D] | L-PEPTIDE LINKING | C15 H15 N O2 | PHE |
Length ( Å ) | Angle ( ˚ ) |
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a = 53.25 | α = 90 |
b = 105.17 | β = 90 |
c = 117.07 | γ = 90 |
Software Name | Purpose |
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PHENIX | refinement |
XDS | data reduction |
XSCALE | data scaling |
MOLREP | phasing |