Structure of HEMK2-TRM112 Complex with SAM
Guo, Q., Liao, S., Xu, C.To be published.
Experimental Data Snapshot
Starting Models: experimental
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Entity ID: 1 | |||||
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Molecule | Chains | Sequence Length | Organism | Details | Image |
Methyltransferase N6AMT1 | 216 | Homo sapiens | Mutation(s): 0  Gene Names: N6AMT1 EC: 2.1.1 (PDB Primary Data), 2.1.1.72 (PDB Primary Data) | ||
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for Q9Y5N5 (Homo sapiens) Explore Q9Y5N5  Go to UniProtKB:  Q9Y5N5 | |||||
PHAROS:  Q9Y5N5 GTEx:  ENSG00000156239  | |||||
Entity Groups   | |||||
Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
UniProt Group | Q9Y5N5 | ||||
Sequence AnnotationsExpand | |||||
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Entity ID: 2 | |||||
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Molecule | Chains | Sequence Length | Organism | Details | Image |
Multifunctional methyltransferase subunit TRM112-like protein | 125 | Homo sapiens | Mutation(s): 0  Gene Names: TRMT112 | ||
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for Q9UI30 (Homo sapiens) Explore Q9UI30  Go to UniProtKB:  Q9UI30 | |||||
PHAROS:  Q9UI30 GTEx:  ENSG00000173113  | |||||
Entity Groups   | |||||
Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
UniProt Group | Q9UI30 | ||||
Sequence AnnotationsExpand | |||||
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Ligands 1 Unique | |||||
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ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
SAM (Subject of Investigation/LOI) Query on SAM | C [auth A] | S-ADENOSYLMETHIONINE C15 H22 N6 O5 S MEFKEPWMEQBLKI-FCKMPRQPSA-N |
Length ( Å ) | Angle ( ˚ ) |
---|---|
a = 109.607 | α = 90 |
b = 109.607 | β = 90 |
c = 130.368 | γ = 120 |
Software Name | Purpose |
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PHENIX | refinement |
HKL-3000 | data reduction |
HKL-3000 | data scaling |
PHENIX | phasing |