Download MendeleyTrypanosoma cruzi farnesyl diphosphate synthase in complex with IPP and Mn
Magari, F., Heine, A., Klebe, G.To be published.
6T7N
Trypanosoma cruzi farnesyl diphosphate synthase in complex with IPP and Mn
- PDB DOI: https://doi.org/10.2210/pdb6T7N/pdb
- Classification: TRANSFERASE
- Organism(s): Trypanosoma cruzi
- Expression System: Escherichia coli BL21(DE3)
- Mutation(s): No
- Deposited: 2019-10-22 Released: 2020-11-18
- Funding Organization(s): European Union
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 1.90 Å
- R-Value Free: 0.208
- R-Value Work: 0.173
- R-Value Observed: 0.175
This is version 1.1 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Farnesyl diphosphate synthase | A [auth AAAA] | 362 | Trypanosoma cruzi | Mutation(s): 0 |  |
UniProt | |||||
Find proteins for Q8WS26 (Trypanosoma cruzi) Explore Q8WS26 Go to UniProtKB: Q8WS26 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | Q8WS26 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 2 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| IPE (Subject of Investigation/LOI) Query on IPE | E [auth AAAA], F [auth AAAA] | 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE C5 H12 O7 P2 NUHSROFQTUXZQQ-UHFFFAOYSA-N |  | ||
| MN Query on MN | B [auth AAAA], C [auth AAAA], D [auth AAAA] | MANGANESE (II) ION Mn WAEMQWOKJMHJLA-UHFFFAOYSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 1.90 Å
- R-Value Free: 0.208
- R-Value Work: 0.173
- R-Value Observed: 0.175
- Space Group: P 61 2 2
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 58.45 | α = 90 |
| b = 58.45 | β = 90 |
| c = 391.793 | γ = 120 |
| Software Name | Purpose |
|---|---|
| PHENIX | refinement |
| XDS | data reduction |
| XDS | data scaling |
| SHELXDE | phasing |
Entry History & Funding Information
Deposition Data
- Released Date: 2020-11-18 Deposition Author(s): Magari, F., Heine, A., Klebe, G.
| Funding Organization | Location | Grant Number |
|---|---|---|
| European Union | -- |
Revision History (Full details and data files)
- Version 1.0: 2020-11-18
Type: Initial release - Version 1.1: 2024-05-15
Changes: Data collection, Database references
