Download MendeleySalmonella typhimurium mutant neuraminidase (D100S)+ DANA
Garman, E.F., Salinger, M.T., Murray, J.W., Laver, W.G., Kuhn, P., Vimr, E.R.To be published.
6TVI
Salmonella typhimurium mutant neuraminidase (D100S)+ DANA
- PDB DOI: https://doi.org/10.2210/pdb6TVI/pdb
- Classification: HYDROLASE
- Organism(s): Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
- Expression System: Escherichia coli
- Mutation(s): Yes
- Deposited: 2020-01-09 Released: 2020-02-12
- Funding Organization(s): Medical Research Council (United Kingdom)
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 1.00 Å
- R-Value Free: 0.133
- R-Value Work: 0.118
Starting Model: experimental
View more details
This is version 1.2 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Sialidase | A [auth AAA] | 379 | Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 | Mutation(s): 1 Gene Names: nanH, STM0928 EC: 3.2.1.18 |  |
UniProt | |||||
Find proteins for P29768 (Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)) Explore P29768 Go to UniProtKB: P29768 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P29768 | ||||
Sequence AnnotationsExpand | |||||
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Small Molecules
| Ligands 2 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| DAN Query on DAN | H [auth AAA] | 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID C11 H17 N O8 JINJZWSZQKHCIP-UFGQHTETSA-N |  | ||
| GOL Query on GOL | B [auth AAA] C [auth AAA] D [auth AAA] E [auth AAA] F [auth AAA] | GLYCEROL C3 H8 O3 PEDCQBHIVMGVHV-UHFFFAOYSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 1.00 Å
- R-Value Free: 0.133
- R-Value Work: 0.118
- Space Group: P 21 21 21
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 47.068 | α = 90 |
| b = 81.781 | β = 90 |
| c = 91.065 | γ = 90 |
| Software Name | Purpose |
|---|---|
| REFMAC | refinement |
| MOSFLM | data reduction |
| SCALA | data scaling |
| REFMAC | phasing |
Entry History & Funding Information
Deposition Data
- Released Date: 2020-02-12 Deposition Author(s): Garman, E.F., Salinger, M.T., Murray, J.W., Laver, W.G., Kuhn, P., Vimr, E.R.
| Funding Organization | Location | Grant Number |
|---|---|---|
| Medical Research Council (United Kingdom) | United Kingdom | -- |
Revision History (Full details and data files)
- Version 1.0: 2020-02-12
Type: Initial release - Version 1.1: 2020-07-29
Type: Remediation
Reason: Carbohydrate remediation
Changes: Data collection - Version 1.2: 2024-01-24
Changes: Data collection, Database references, Derived calculations, Refinement description, Structure summary
