Crystal structure of MurE from E.coli
Koekemoer, L., Steindel, M., Fairhead, M., Talon, R., Douangamath, A., Arrowsmith, C.H., Edwards, A.M., Bountra, C., von Delft, F., Krojer, T.To be published.
Experimental Data Snapshot
Starting Model: experimental
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Entity ID: 1 | |||||
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Molecule | Chains | Sequence Length | Organism | Details | Image |
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-2,6-diaminopimelate ligase | 496 | Escherichia coli K-12 | Mutation(s): 0  Gene Names: murE, b0085, JW0083 EC: 6.3.2.13 | ||
UniProt | |||||
Find proteins for P22188 (Escherichia coli (strain K12)) Explore P22188  Go to UniProtKB:  P22188 | |||||
Entity Groups   | |||||
Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
UniProt Group | P22188 | ||||
Sequence AnnotationsExpand | |||||
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Ligands 2 Unique | |||||
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ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
LVV (Subject of Investigation/LOI) Query on LVV | C [auth A], D [auth A], G [auth B], H [auth B] | 4-[(4-methylphenyl)methyl]-1,4-thiazinane 1,1-dioxide C12 H17 N O2 S PBEMXBVPRZGFNM-UHFFFAOYSA-N | |||
DMS Query on DMS | E [auth A], F [auth A], I [auth B] | DIMETHYL SULFOXIDE C2 H6 O S IAZDPXIOMUYVGZ-UHFFFAOYSA-N |
Length ( Å ) | Angle ( ˚ ) |
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a = 58.283 | α = 97.08 |
b = 58.403 | β = 91.46 |
c = 73.882 | γ = 105.59 |
Software Name | Purpose |
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REFMAC | refinement |
xia2 | data reduction |
xia2 | data scaling |
PHASER | phasing |